Disease

MIT researchers created this colon tumor by delivering RNA encapsulated in lipid nanoparticles to the colon. The RNA can activate or delete specific genes, leading to tumor growth.

New model could speed up colon cancer research

Introducing genetic mutations with CRISPR offers a fast and accurate way to simulate the disease.

May 1, 2017

Hadley Sikes, an associate professor in the Department of Chemical Engineering, is one of an increasing number of MIT faculty members who do what might best be called public engineering — emphasizing the interaction between society and technology.

The creation of a public engineer

Hadley Sikes is bridging the gap between engineering and public policy to solve big social problems at home and abroad.

April 27, 2017

A deconvolved wide-field fluorescence microscope image of human HeLa cancer cells, during late anaphase/early telophase, showing a lagging chromosome. If this fails to get into a daughter cell, it may lead to aneuploidy.

Study helps explain varying outcomes for cancer, Down Syndrome

Differences in chromosome number may underlie variation among genetically identical individuals.

April 6, 2017

A new safety test for foodborne pathogens is based on a novel type of liquid droplet that can bind to bacterial proteins. This interaction, which can be detected by either the naked eye or a smartphone, could offer a much faster and cheaper alternative to existing food safety tests.

New technology could offer cheaper, faster food testing

Specialized droplets interact with bacteria and can be analyzed using a smartphone.

April 5, 2017

Collaborative research by Bradley Pentelute, the Pfizer-Laubach Career Development Associate Professor in Chemistry, and scientists at UCLA and Harvard Medical School, used cryo-electron microscopy to understand the mechanisms behind anthrax bacteria toxin delivery system (shown here).

MIT receives $7.5 million to enhance structural biology research

Beckman Foundation grant helps secure cryo-electron microscopy at MIT.nano facility.

April 4, 2017

In a study of 365,000 NIH grants — nearly every NIH grant awarded for 27 years — researchers found that 31 percent produce articles that are later cited by patents in the biomedical sector.

Study: NIH funding generates large numbers of private-sector patents

New research shows large spillover from the lab to commercial activity.

March 30, 2017

MIT researchers have devised a new vaccine candidate for the Zika virus. “It functions almost like a synthetic virus, except it’s not pathogenic and it doesn’t spread,” says postdoc Omar Khan.

Progress toward a Zika vaccine

Researchers program RNA nanoparticles that could protect against the virus.

March 29, 2017

Research scientist Bogdan Fedeles and postdoc Supawadee Chawanthayatham have discovered a mutational signature that reveals liver cell exposure to aflatoxin, a potent carcinogen.

Detecting mutations could lead to earlier liver cancer diagnosis

New technique can reveal exposure to aflatoxin, a potent carcinogen, before tumors develop.

March 27, 2017

A new paper from an MIT-led team demonstrates that Alaska can offer a significant foothold for Asian flu viruses, enabling them to enter North America.

Tracking the spread of bird flu

Asian flu strains can enter North America through Alaska, study finds.

March 17, 2017

A raindrop, splashing on a porous surface, can release thousands of aerosols, as captured here in high-speed imaging experiments.

A light rain can spread soil bacteria far and wide, study finds

Global precipitation may account for 1 to 25 percent of bacteria emitted from land.

March 7, 2017

After feeding C. elegans worms an equal mix of bacteria that express either red or green fluorescent protein, MIT researchers found that the microbial populations in the worms’ digestive tracts tend to become dominated by one or the other.

Microbiome diversity is influenced by chance encounters

Study finds a role for randomness in the composition of the gut’s microbe populations.

March 3, 2017

A new MIT transmitter that measures dopamine overcomes limitations of earlier transmitters, providing accurate readings for longer periods of time and covering more of the brain.

Precise technique tracks dopamine in the brain

New sensor could reveal the neurotransmitter’s role in learning and habit formation.

March 3, 2017

A team of MIT biological engineers has developed a method to measure levels of the iron-containing protein heme inside the malaria parasite. “One of our long-term goals is ultimately being able to tie insights from these studies back to thinking about drug discovery and targeting pathways that regulate heme,” says Jacquin Niles, an MIT associate professor of biological engineering.

Taking aim at a key malaria molecule

Measuring the parasite’s heme levels could help scientists develop better antimalarial drugs.

February 27, 2017

Eight student teams pitched novel inventions at last night’s MIT Sloan Healthcare Innovations Prize pitch competition. Rendever earned the $25,000 grand prize for creating a virtual-reality platform that gives the elderly the chance to explore the world virtually. The platform also provides cognitive therapy and tracks movement data to aid in early diagnosis of dementia.

Virtual-reality system for the elderly wins health care prize

Eight student teams pitched novel inventions at MIT Sloan Healthcare Innovations Prize competition.

February 24, 2017

How the U.S. can beat hepatitis C: Don’t buy the pills, buy the company

Pharma veteran and MIT visiting scientist Mark Trusheim advances a provocative solution to overcome treatment costs.

January 20, 2017

MIT News | Massachusetts Institute of Technology

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