Cancer

A new technique prevents cell-killing proteins called cytokines from escaping once they have been injected into a tumor.

Confining cell-killing treatments to tumors

Attaching a Velcro-like molecule may prevent immune proteins called cytokines from leaking out of cancerous tissue after injection.

June 26, 2019

MIT biologists have identified a drug that blocks a DNA repair pathway used by cancer cells, making them more susceptible to chemotherapy drugs that damage DNA.

Drug makes tumors more susceptible to chemo

Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.

June 6, 2019

Aneuploid cells, such as this one, have too few or too many chromosomes. A new study has revealed that highly aneuploid prostate tumors carry a higher risk of lethality.

Measuring chromosome imbalance could clarify cancer prognosis

A study of prostate cancer finds “aneuploid” tumors are more likely to be lethal than tumors with normal chromosome numbers.

May 13, 2019

The team's model was shown to be able to identify a woman at high risk of breast cancer four years (left) before it developed (right).

Using AI to predict breast cancer and personalize care

MIT/MGH's image-based deep learning model can predict breast cancer up to five years in advance.

May 7, 2019

3Q: Susan Hockfield on a new age of living machines

Convergence research at MIT and beyond seeks new solutions for global challenges.

May 7, 2019

Researchers at the Koch Institute for Integrative Cancer Research at MIT have developed a new approach to targeting tumors and metastases.

A new approach to targeting tumors and tracking their spread

Researchers develop nanosized antibodies that home in on the meshwork of proteins surrounding cancer cells.

May 6, 2019

2019 Science Slam participants, hosts, and judges (left to right): Jay Thangappan, Tyler Smith, Darren Parker, Rebecca Silberman, Arish Shah, Sophia Xu, Monika Avello, Jasmin Imran Alsous, John Pham, Lindsey Backman, Emma Kowal, Ari Daniel, Vivian Siegel, and Mary Carmichael.

Department of Biology hosts second annual Science Slam

Eight biology contestants get one slide and three minutes to explain their research and impress their listeners.

April 29, 2019

MIT engineers have designed a magnetic microrobot that can help push drug-delivery particles into tumor tissue (left). They also employed swarms of naturally magnetic bacteria to achieve the same effect (right).

Nanoparticles take a fantastic, magnetic voyage

Tiny robots powered by magnetic fields could help drug-delivery nanoparticles reach their targets.

April 26, 2019

Researchers at MIT and MGH have developed an image-guided surgical system that could help surgeons better visualize and remove tiny ovarian tumors. Fluorescent carbon nanotubes are used as probes to bind to the tumors, making them easier to see.

Imaging system helps surgeons remove tiny ovarian tumors

More effective surgery could boost survival rates for ovarian cancer.

April 23, 2019

Pancreatic cancer cells (nuclei in blue) growing as a sphere encased in membranes (red). By growing cancer cells in the lab, researchers can study factors that promote and prevent the formation of deadly tumors.

The fluid that feeds tumor cells

The substance that bathes tumors in the body is quite different from the medium used to grow cancer cells in the lab, biologists report.

April 16, 2019

A group of academic institutions has granted a license for SHERLOCK, the highly-sensitive, low-cost CRISPR-based diagnostic, for commercial uses in the developed world, while reserving rights to enable its broad use by organizations to serve developing nations as well as unmet public health needs in the developed world.

Academic institutions grant commercial license for CRISPR-based SHERLOCK diagnostic technology in developed world

Rights are protected for broad use in developing world and for public health needs.

March 21, 2019

In these tumor cells, acidic regions are labeled in red. Invasive regions of the cells, which express a protein called MMP14, are labeled in green.

How tumors behave on acid

Acidic environment triggers genes that help cancer cells metastasize.

March 20, 2019

Using machine learning for medical solutions

Master’s student and Marshall Scholar Kyle Swanson uses computer science to help make drug development more efficient.

March 19, 2019

MIT researchers have discovered a way to manipulate the interactions of the proteins Myc and Max, which regulate gene transcription. At left, Myc interacts with Max, at center, Max is alone, at right, two molecules of Max.

A new approach to drugging a difficult cancer target

Study suggests an alternative way to treat tumors that are dependent on the cancer-promoting Myc protein.

March 14, 2019

MIT researchers have devised a way to simultaneously image in multiple wavelengths of near-infrared light, allowing them to determine the depth of particles emitting different wavelengths.

New optical imaging system could be deployed to find tiny tumors

Near-infrared technology pinpoints fluorescent probes deep within living tissue; may be used to detect cancer earlier.

March 7, 2019

MIT News | Massachusetts Institute of Technology

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