A new wave of treatment for Alzheimer’s disease
Professor Li-Huei Tsai studies how brain waves can be used to treat neurodegenerative diseases such as Alzheimer’s.
Exploring the links between diet and cancer
Omer Yilmaz’s work on how diet influences intestinal stem cells could lead to new ways to treat or prevent gastrointestinal cancers.
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state
Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.
“SCOUT” helps researchers find, quantify significant differences among organoids
Unbiased, high-throughput analysis pipeline improves utility of “minibrains” for understanding development and diseases such as Zika infection.
Study finds path for addressing Alzheimer’s blood-brain barrier impairment
MIT researchers pinpoint mechanism and demonstrate that drugs could help.
Study links certain metabolites to stem cell function in the intestine
Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue.
Helping blood cells regenerate after radiation therapy
Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.
In pursuit of the elusive stem cell
New MIT initiative delves into the biology of stem cells and cancer stem cells, seeks ways to identify, purify, and propagate them.
Charting a path to better cell models of the intestine
Researchers generate an intestinal cell mimic that can be harnessed in studies of diseases such as inflammatory bowel disease.
A blueprint for regeneration
Whitehead Institute researchers uncover framework for how stem cells determine where to form replacement structures.
Biologists identify key step in lung cancer evolution
Blocking the transition to a more aggressive state could offer a new treatment strategy.
Drug treatment could combat hearing loss
Researchers discover a drug combination that can regenerate hair cells in the inner ear.
How diet influences colon cancer
Study ties high-fat diet to changes in intestinal stem cells, may help explain increased cancer risk.
Organ-on-a-chip
In a step toward personalized drug testing, researchers coax human stem cells to form complex tissues.
From the heart
Laurie Boyer’s studies of stem cell differentiation could improve treatments for heart disease.