Singapore-MIT Alliance for Research and Technology (SMART)

SMART AMR researcher Hooi Linn Loo prepares immune cells.

SMART research enhances dengue vaccination in mice

Sequential immunization might be safer and more effective than the existing tetravalent vaccine.

August 11, 2020

“Traditional drug development processes are very linear, and they take many years,” says MIT Professor Ram Sasisekharan, pictured here. “If you’re going to get something to humans fast, you can’t do it linearly, because then the best-case scenario for testing in humans is a year to 18 months. If you need to develop a drug in six months or less, then a lot of these things need to happen i...

Rapid antibody development yields possible treatment for yellow fever

The experimental drug has shown promise in early-stage clinical trials conducted in Singapore.

July 29, 2020

SMART researchers found that in Chengdu, China, one-third of ride-sourcing substitutes for public transit trips.

Does ride-sharing substitute for or complement public transit?

In the Chinese city of Chengdu, one-third of ride-sharing might replace public transit trips.

July 27, 2020

3M is collaborating with the lab of MIT Associate Professor Hadley Sikes to jointly develop a rapid Covid-19 test. Here, 3M Covid-19 test team members work in a pilot lab facility.

MIT team collaborates with 3M to develop rapid Covid-19 test

Company working with Sikes Lab to test feasibility of low-cost diagnostic that could be manufactured by the millions each day.

July 14, 2020

In this photo, Alison Hoyt stands on top of a log during a research trip in a peat swamp forest in Borneo. Tropical peatlands are permanently flooded forest lands, where the debris of fallen leaves and branches is preserved by the wet environment and continues to accumulate for centuries, rather than continually decomposing as it does in dryland forests.

Peatland drainage in Southeast Asia adds to climate change

Study reveals drainage, deforestation of the region’s peatlands, which leads to fires, greenhouse emissions, land subsidence.

June 4, 2020

An MIT study shows that electrical vehicle batteries could have a useful and profitable second life as backup storage for grid-scale solar photovoltaic installations, where they could perform for more than a decade in this less demanding role. This image shows a ‘cut-away’ view of a lithium-ion battery over a background of cars and solar panels.

Solar energy farms could offer second life for electric vehicle batteries

Modeling study shows battery reuse systems could be profitable for both electric vehicle companies and grid-scale solar operations.

May 22, 2020

A SMART Antimicrobial Resistance Interdisciplinary Research Group scientist optimizes a prototype assay.

SMART researchers receive grant to develop rapid tests for Covid-19

Using engineered binder proteins to detect viral proteins or antibodies rather than RNA, new tests may overcome current challenges in testing for SARS-CoV-2 virus.

May 19, 2020

Hadley Sikes, who recently earned tenure in MIT’s Department of Chemical Engineering, devotes much of her lab’s effort to devising inexpensive, highly sensitive tests for diseases such as malaria, tuberculosis, and cancer.

Making an impact through chemical engineering

Hadley Sikes designs simple-to-use diagnostic devices that could benefit patients around the world.

May 18, 2020

By replacing oxygen with sulfur in the DNA backbone to make a phosphorothioate modification, bacteria protect their DNA from invading viruses without changing the genetic code in the DNA.

SMART researchers uncover new anti-phage defense mechanisms

Discovery explains why some bacteria have been able to defend against phage therapy, opens new ways to overcome existing challenges.

May 13, 2020

SMART Antimicrobial Resistance Interdisciplinary Research Group and Low Energy Electronic Systems researchers (l-r) Hadley Sikes, Jia Huan, Tonio Buonassisi, and Isaac Siyu Tian optimize materials used in rapid protein tests.

3 Questions: Hadley Sikes on searching for a Covid-19 protein test

Chemical engineer aims to create a test that can work in 10 minutes and doesn’t require specialized instruments or laboratory infrastructure.

April 17, 2020

MIT chemical engineers have designed a sensor that can be embedded into plant leaves and measure hydrogen peroxide levels, which indicate that damage has occurred. The signal can be sent to a nearby smartphone.

Nanosensor can alert a smartphone when plants are stressed

Carbon nanotubes embedded in leaves detect chemical signals that are produced when a plant is damaged.

April 15, 2020

A new embedded droplet printing method suspends 3D arrays of droplets in a uniquely isolated state that allows for precise processing and experimentation.

SMART announces new method for processing fluid droplets

Microfluidics enables researchers to create unique environment for developing medicine, paving the way for more potent, high-quality drugs.

March 16, 2020

Perovskites, a family of materials defined by a particular kind of molecular structure as illustrated here, have great potential for new kinds of solar cells. A new study from MIT shows how these materials could gain a foothold in the solar marketplace.

Researchers develop a roadmap for growth of new solar cells

Starting with higher-value niche markets and then expanding could help perovskite-based solar panels become competitive with silicon.

February 6, 2020

Currently, 90 percent of the world’s solar panels are made from crystalline silicon, and the industry continues to grow at a rate of about 30 percent per year.

For cheaper solar cells, thinner really is better

Solar panel costs have dropped lately, but slimming down silicon wafers could lead to even lower costs and faster industry expansion.

January 26, 2020

This sensor can measure blood glucose levels noninvasively by shining near-infrared light through the skin and measuring the chemical composition of the tissue below.

Researchers hope to make needle pricks for diabetics a thing of the past

Study suggests noninvasive spectroscopy could be used to monitor blood glucose levels.

January 24, 2020

MIT News | Massachusetts Institute of Technology

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