Q&A: Markus Buehler on setting coronavirus and AI-inspired proteins to music
Translated into sound, SARS-CoV-2 tricks our ear in the same way the virus tricks our cells.
Biologists build proteins that avoid crosstalk with existing molecules
Engineered signaling pathways could offer a new way to build synthetic biology circuits.
Understanding genetic circuits and genome organization
Assistant professors Pulin Li and Seychelle Vos are investigating how cells become tissues and the proteins that organize DNA.
Cleaning up hydrogen peroxide production
Solugen’s engineered enzymes offer a biologically-inspired method for producing the chemical.
Characterizing tau aggregates in neurodegenerative diseases
New research reveals a structural model for amyloid fibrils that could aid in future medicinal interventions for Alzheimer's, CTE, and more.
How brain cells pick which connections to keep
Novel study shows protein CPG15 acts as a molecular proxy of experience to mark synapses for stabilization.
Speeding up drug discovery for brain diseases
Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.
Translating proteins into music, and back
By turning molecular structures into sounds, researchers gain insight into protein structures and create new variations.
A “biomultimeter” lets scientists measure RNA and protein production in real-time
Fluorescent tagging system can expedite the process of designing genes and personalizing medicine.
Predicting sequence from structure
Researchers have devised a faster, more efficient way to design custom peptides and perturb protein-protein interactions.
Enhanced NMR reveals chemical structures in a fraction of the time
Technique could yield insights into complex proteins involved in Alzheimer’s and other diseases.
Protein has unique effects on information processing
Picower Institute researchers find that a key protein linked to intellectual disability shapes electrical currents in neural connections.
Scientists alter membrane proteins to make them easier to study
By making hydrophobic sections water-soluble, researchers hope to learn more about protein structures.
Researchers decode molecule that gives living tissues their flexibility
Study reveals atomic structure of tropoelastin, showing what goes wrong in some diseases.
Structure of key growth regulator revealed
Researchers identify the molecular structure of the GATOR1 protein complex, which regulates growth signals in human cells, using cryo-electron microscopy.