Enhancing activity of a specific component of neurons’ “NMDA” receptors normalized protein synthesis, neural activity, and seizure susceptibility in the hippocampus of fragile X lab mice.
New methods light up lipid membranes and let researchers see sets of proteins inside cells with high resolution.
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
FragFold, developed by MIT Biology researchers, is a computational method with potential for impact on biological research and therapeutic applications.
Whitehead Institute and CSAIL researchers created a machine-learning model to predict and generate protein localization, with implications for understanding and remedying disease.
Tissue processing advance can label proteins at the level of individual cells across large samples just as fast and uniformly as in dissociated single cells.
Chronic diseases like diabetes are prevalent, costly, and challenging to treat. A common denominator driving them may be a promising new therapeutic target.
Through academia and industry, Gevorg Grigoryan PhD ’07 says there is no right path — just the path that works for you.
A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.
Researchers created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics.
An atlas of human protein kinases enables scientists to map cell signaling pathways with unprecedented speed and detail.
MIT researchers plan to search for proteins that could be used to measure electrical activity in the brain.
Software allows scientists to model shapeshifting proteins in native cellular environments.
Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.
Brad Pentelute and his lab compel the anthrax delivery system to deliver antibody and peptide variants into cells to treat cancer.