National Institutes of Health (NIH)

Researchers have created a new type of dual-sided pill that attaches to the gastrointestinal tract. One side of the pill sticks to mucosal surfaces, while the other is omniphobic, meaning that it repels everything it encounters.

Engineers develop a pill for long-term drug release

New tablet attaches to the lining of the GI tract, resists being pulled away.

April 6, 2016

The brain’s thalamic reticular nucleus (TRN), highlighted in the center, is responsible for blocking out distracting sensory input. "For autism, schizophrenia, and other neurodevelopmental disorders, it seems like TRN dysfunction may be involved in some patients,” Guoping Feng says.

Study reveals a basis for attention deficits

New findings could help scientists develop treatments for ADHD and other disorders.

March 23, 2016

A scanning electron micrograph of a nanocrystal superlattice shows long-range ordering over large domains.

Nanocrystal self-assembly sheds its secrets

A new approach gives a real-time look at how the complex structures form.

March 21, 2016

This image depicts the process of metastasis in a mouse tumor, where tumor cells (green) have helped to reorganize the collagen into aligned fibers (blue) that provide the structural support for motility. This helps the tumor cells to enter blood vessels (red), ultimately leading to the formation of metastases in other organs.

Paving the way for metastasis

Cancer cells remodel their environment to make it easier to reach nearby blood vessels.

March 15, 2016

Artist interpretation of a cancer cell dividing

How cancer cells fuel their growth

Scientists surprised to find amino acids, not sugar, supply most building blocks for tumor cells.

March 7, 2016

"[W]e hope that our studies of vps-50 will provide insights into human neuropsychiatric disorders,” H. Robert Horvitz says.

Neuroscientists discover a gene that controls worms’ behavioral state

Gene required for the control of behavioral state is also found in humans, may be linked to autism.

March 3, 2016

A stealth material surface, shown here, has been engineered to provide an “invisibility cloak” against the body’s immune system cells. In this electron microscopy image, you can see the material's surface topography.

No more insulin injections?

Encapsulated pancreatic cells offer possible new diabetes treatment.

January 25, 2016

Researchers have discovered how some organisms can safely process oxalate, which is found in many fruits and vegetables. This discovery could lead to new ways to lessen the harmful effects that can occur when oxalate builds up in humans, who cannot metabolize this molecule.

A healthy breakdown

Researchers discover how some organisms process oxalate, a molecule that can harm humans.

December 28, 2015

Matthew Shoulders receives NIH director's New Innovator Award

Seventy-eight grants awarded to scientists proposing highly innovative approaches to major contemporary challenges in biomedical research.

October 16, 2015

Amyloidal structure created with the Matriarch software.

A new molecular design approach

New programming tool could help engineers build biologically inspired materials.

September 11, 2015

Study: Firms “underinvest” in long-term cancer research

Tweaks to the R&D pipeline could create new drugs and greater social benefit.

July 28, 2015

Shiyi Zhang, a postdoc at the Koch Institute and the paper’s lead author, holds a ring-shaped device prototype (left), which can be folded into a swallowable capsule (right) for easy and safe oral delivery.

New material opens possibilities for super-long-acting pills

A pH-responsive polymer gel could create swallowable devices, including capsules for ultra-long drug delivery.

July 27, 2015

Spit take

A newly discovered feeding behavior in worms could shed light on human heart function.

July 23, 2015

Illustrated brain with colored lights inside

Uncovering a dynamic cortex

Neuroscientists show that multiple cortical regions are needed to process information.

June 18, 2015

Photo shows the open lattice of 3-D printed material, with materials having different characteristics of strength and flexibility indicated by different colors.

Tough biogel structures produced by 3-D printing

Stretchable, biocompatible hydrogels with complex patterning could be used in tissue engineering.

June 1, 2015

MIT News | Massachusetts Institute of Technology

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