National Institutes of Health (NIH)

MIT Professor Tyler Jacks, director of the Koch Institute for Integrative Cancer Research, recently testified before a U.S. House Committee on Oversight and Government Reform hearing titled, “Federally Funded Cancer Research: Coordination and Innovation.” He is seen here presenting recommendations from the Cancer Moonshot Blue Ribbon Panel report to the National Cancer Advisory Board in Septem...

Tyler Jacks: NIH budget cuts would have “devastating” effects on progress against cancer

Koch Institute director advocates support for biomedical research in testimony before the House Committee on Oversight and Government Reform.

April 10, 2017

Researchers have found a way to make tiny particles that can be injected into the body, where they emit short-wave infrared light. The advance may open up a new way of making detailed images of internal body structures such as fine networks of blood vessels.

Nanoparticles open new window for biological imaging

“Quantum dots” that emit infrared light enable highly detailed images of internal body structures.

April 10, 2017

In a study of 365,000 NIH grants — nearly every NIH grant awarded for 27 years — researchers found that 31 percent produce articles that are later cited by patents in the biomedical sector.

Study: NIH funding generates large numbers of private-sector patents

New research shows large spillover from the lab to commercial activity.

March 30, 2017

Scientists identify brain circuit that drives pleasure-inducing behavior

Surprisingly, the neurons are located in a brain region thought to be linked with fear.

March 22, 2017

The immune system often builds up a wall of dense scar tissue around implanted medical devices, a process known as fibrosis. The cell shown in blue represents a macrophage that has been blocked from initiating fibrosis.

Study points a way to better implants

Selectively blocking immune cells can prevent formation of scar tissue around medical devices.

March 20, 2017

A new MIT transmitter that measures dopamine overcomes limitations of earlier transmitters, providing accurate readings for longer periods of time and covering more of the brain.

Precise technique tracks dopamine in the brain

New sensor could reveal the neurotransmitter’s role in learning and habit formation.

March 3, 2017

A team of MIT biological engineers has developed a method to measure levels of the iron-containing protein heme inside the malaria parasite. “One of our long-term goals is ultimately being able to tie insights from these studies back to thinking about drug discovery and targeting pathways that regulate heme,” says Jacquin Niles, an MIT associate professor of biological engineering.

Taking aim at a key malaria molecule

Measuring the parasite’s heme levels could help scientists develop better antimalarial drugs.

February 27, 2017

Obstructive sleep apnea is caused by a narrowing of the airway that cuts off breathing, and people who are obese are at higher risk for the disorder. MIT researchers have discovered that a dietary supplement called yohimbine reverses the root cause of obstructive sleep apnea in an animal model.

A possible new approach to stopping obstructive sleep apnea

Dietary supplement derived from tree bark shows promise for treating the disorder.

February 23, 2017

This image shows large clonal colonies of cochlear progenitor cells formed from single cells and converted into high-purity colonies of hair cells (cyan) with intricate hair bundles (red).

Drug treatment could combat hearing loss

Researchers discover a drug combination that can regenerate hair cells in the inner ear.

February 21, 2017

Researchers have found that the hydrogel’s mostly watery environment helps keep nutrients and programmed bacteria alive and active. When the bacteria reacts to a certain chemical, the bacteria are programmed to light up, as seen on the left.

Living sensors at your fingertips

Cell-infused gloves and bandages light up when in contact with certain chemicals.

February 15, 2017

This high-resolution transmission electron micrograph of particles made by the research team shows the particles’ highly uniform size and shape. These are iron oxide particles just 3 nanometers across, coated with a zwitterion layer. Their small size means they can easily be cleared through the kidneys after injection.

A new contrast agent for MRI

New iron oxide nanoparticles could help avoid a rare side effect caused by current contrast agents.

February 14, 2017

MIT researchers have developed a portable technology, known as Seq-Well, that can rapidly prepare the RNA of many cells for sequencing simultaneously.

Making single-cell RNA sequencing widely available

Portable tool could help scientists learn more about cells’ roles in many diseases.

February 13, 2017

A team of researchers from MIT, Georgia Tech, and the University of Florida has devised a way to rapidly test different nanoparticles to see where they go in the body.

Nanoparticle screen could speed up drug development

New test helps identify particles for gene delivery or RNA interference.

February 7, 2017

MIT chemical engineers have developed an extremely sensitive detector that can track single cells’ secretion of dopamine. These video stills show a single cell releasing dopamine.

Sensor traces dopamine released by single cells

New technology could help neuroscientists understand how dopamine influences brain activity.

February 6, 2017

Researchers at MIT and Brigham and Women’s Hospital have designed and demonstrated a small, ingestible voltaic cell that is sustained by the acidic fluids in the stomach.

Engineers harness stomach acid to power tiny sensors

Ingestible electronic devices could monitor physiological conditions or deliver drugs.