In health care, does “hotspotting” make patients better?
Study shows no effect from program intended to reduce repeated hospitalizations by targeting high-cost patients.
“She” goes missing from presidential language
Even when people believed Hillary Clinton would win the 2016 election, they did not use “she” to refer to the next president.
Screen could offer better safety tests for new chemicals
Using specialized liver cells, a new test can quickly detect potentially cancer-causing DNA damage.
New health insurance insights
Economists analyze how patients and health care providers value Medicaid.
A new way to regulate gene expression
Biologists uncover an evolutionary trick to control gene expression that reverses the flow of genetic information from RNA splicing back to transcription.
New treatment could ease the passage of kidney stones
Muscle relaxants delivered to the ureter can reduce contractions that cause pain when passing a stone.
Taking a moonshot at a rare childhood cancer
Team of researchers including MIT Professor Angela Koehler obtains $5.8 million grant to study fusion-positive alveolar rhabdomyosarcoma.
Technique identifies T cells primed for certain allergies or infections
Researchers develop a method to isolate and sequence the RNA of T cells that react to a specific target.
Nanoparticle orientation offers a way to enhance drug delivery
Coating particles with “right-handed” molecules could help them penetrate cancer cells more easily.
New synthesis method yields degradable polymers
Materials could be useful for delivering drugs or imaging agents in the body; may offer alternative to some industrial plastics.
Eric Alm and Peter Dedon receive NIH Transformative Research Award
Award will support interdisciplinary research on the role of the human microbiome in health and disease.
Biologists build proteins that avoid crosstalk with existing molecules
Engineered signaling pathways could offer a new way to build synthetic biology circuits.
Drug combination reverses hypersensitivity to noise
Findings in mice suggest targeting certain brain circuits could offer new ways to treat some neurological disorders.
Whitehead Institute team resolves structure of master growth regulator
New research reveals how mTORC1 docks at lysosomal surface.
Study reveals how mucus tames microbes
Specialized sugar molecules called glycans can disarm opportunistic pathogens and prevent infection.