National Institutes of Health (NIH)

MIT researchers have created “a vibrating pill that stimulates nerve endings in the stomach to tell the brain it’s time to stop eating,” reports Mitch Leslie for Science. “A gel plug in the pill keeps the motor from switching on,” explains Leslie. “But the gel dissolves rapidly when it contacts stomach fluid, allowing the motor to start turning. When that happens, the pill shakes for about 38 minutes, roughly the amount of time it would stay in the stomach. The researchers hypothesized that these vibrations would stimulate the stretch-sensing nerve endings and signal satiety.”

Newsweek reporter Pandora Dewan spotlights MIT researchers and their work developing an ingestible vibrating pill that can mimic the sensation of fullness. "The development of new non-invasive methods for treating obesity is of importance in confronting the multifaceted challenges posed by this global health crisis," says Shriya Srinivasan PhD ’20. "Traditional interventions, such as invasive surgeries, can be associated with significant risks, costs and lifestyle modifications, limiting their applicability and effectiveness.”

Researchers at MIT have developed a vibrating pill that can be swallowed before eating to create a feeling of fullness, reports Nicola Davis for The Guardian. “This approach offers an alternative and potentially synergistic approach to other therapies available today,” says Prof.  Giovanni Traverso.

Researchers at MIT have developed “a battery-operated capsule-like device that’s supposed to make you feel full by stretching out your stomach using vibration,” reports Miriam Fauzia for Inverse. “Considering that diet and exercise are hard to maintain, especially for long-term weight loss, and medical interventions like gastric bypass surgery and the newest wave of injectables cost more than a pretty penny, [Shriya] Srinivasan PhD ’20 and her colleagues want their vibrating pill to be an accessible alternative,” writes Fauzia.

MIT researchers have developed a new cell imaging technique that offers “the ability to observe up to seven different molecules simultaneously,” writes Amal Jos Chacko for Interesting Engineering. “This could open the door to a deeper understanding of cellular functions, aging, and diseases.”

MIT researchers have “used an algorithm to sort through millions of genomes to find new, rare types of CRISPR systems that could eventually be adapted into genome-editing tools,” writes Sara Reardon for Nature. “We are just amazed at the diversity of CRISPR systems,” says Prof. Feng Zhang. “Doing this analysis kind of allows us to kill two birds with one stone: both study biology and also potentially find useful things.”

Researchers from MIT and Harvard have found that an adult’s ability to “parse the early attempts of children to talk may also help the children learn how to speak properly faster,” reports Jess Thomson for Newsweek. “These adult listening abilities might help children communicate very early and highlight that speech is a good way to share information with others," says postdoctoral associate Stephan Meylan. "That said, there is a lot of diversity in how adults and children interact across the world, both within and across different social and cultural contexts. This means that there are very likely many pathways to understanding language."

7 News spotlights how MIT researchers have developed a new implantable device that could provide diabetes patients with insulin without using injections. “What we’ve been able to show is that with a minimally invasive implant that is sitting just under the skin, we’ve actually been able to sort of achieve a diabetic reversal,” explains Research Scientist Siddharth Krishnan.

Gizmodo reporter Ed Cara writes that MIT researchers have developed a new implantable device that can produce its own supply of insulin for up to a month. The team envisions that the device could “eventually be used for other medical conditions dependent on a regular supply of externally produced proteins, such as certain forms of anemia treated with erythropoietin,” writes Cara.

MIT researchers have developed a new implant that in the future could be used to deliver insulin to patients for up to a month, potentially enabling patients to control diabetes without injections, reports Tony Ho Tran for the Daily Beast. In the future, the researchers hope to “develop a device for humans that would be roughly the size of a stick of gum,” writes Tran. “The implant could also be used to deliver things like drugs or proteins to help treat other diseases in humans as well.”

Michal Caspi Tal, a principal research scientist in the department of biological engineering, speaks with Boston Globe reporter Kay Lazar about her research aimed at better understanding why some people develop chronic illness after infection with Lyme disease and Covid-19. “Long Covid and chronic Lyme share so many features that it’s uncanny,” said Tal. “This is a solvable problem. This is not rocket science. This just needs to be looked at with fresh eyes.”

MIT scientists have developed a new brain “atlas” and computer model that sheds insight into the brain-body connections in C. elegans worms, reports Lauren Leffer for Scientific American. “Through establishing those brain-behavior links in a humble roundworm,” writes Leffer, “neuroscientists are one step closer to understanding how all sorts of animal brains, even potentially human ones, encode action.”

Researchers from MIT and Harvard have explored astrocytes, a group of brain cells, from a computational perspective and developed a mathematical model that shows how they can be used to build a biological transformer, reports Kyle Wiggers for TechCrunch. “The brain is far superior to even the best artificial neural networks that we have developed, but we don’t really know exactly how the brain works,” says research staff member Dmitry Krotov. “There is scientific value in thinking about connections between biological hardware and large-scale artificial intelligence networks. This is neuroscience for AI and AI for neuroscience.

MIT researchers at MIT have developed a microfluidic chip-based model of liver tissue that “allows researchers to understand the biological mechanisms underlying liver tissue regeneration and points to several molecules that may promote the process,” reports William A. Haseltine for Forbes. "These results mark significant progress in our understanding of the human body’s regenerative properties," writes Haseltine. 

Researchers at MIT have developed a mobile vaccine printer capable of printing a vaccine onto a patch of microneedles that can be absorbed into the skin without injection, reports Sandra Tsing for NPR. “These printed vaccines could be used in areas that are unable to refrigerate traditional vaccines,” explains Tsing.