Neuroscience

Aera Therapeutics, founded by Prof. Feng Zhang, is working to “debut a type of protein nanoparticle that it believes can be used to ferry all sorts of genetic medicines around the body,” reports Lisa Jarvis for Bloomberg.

Prof. Feng Zhang founded Aera Therapeutics, a startup working to deliver curative genetic medicine to hard-to-reach parts of the body, reports Ryan Cross for The Boston Globe. “If Aera’s approach works in people, it could broaden the reach of genetic therapies, which currently have limited clinical applications – partly because there aren’t enough methods for getting those medicines to hone in on the right cells,” writes Cross.  

Researchers at MIT have developed a drone that can be controlled using hand gestures, reports Mashable. “I think it’s important to think carefully about how machine learning and robotics can help people to have a higher quality of life and be more productive,” says postdoc Joseph DelPreto. “So we want to combine what robots do well and what people do well so that they can be more effective teams.”

Researchers from MIT and elsewhere have studied the mind of polyglots and uncovered how language-specific regions of the brain respond to different and familiar languages, reports Natalia Mesa for Science. The researchers found that “the activity in the brain’s language network fluctuated based on how well participants understood a language. The more familiar the language, the larger the response,” writes Mesa. “There was one exception to the rule: when participants heard their native tongue, their language networks were actually quieter than when they heard other familiar languages.”

Writing for CNBC, senior lecturer Tara Swart shares four tips to avoid brain fog and forgetfulness. “By articulating your goals to yourself out loud, you can start to be more intentional about changing your habits,” writes Swart. “And through that repetition, your brain and body will start to follow suit.”

National Geographic reporter Maya Wei-Haas explores how the ancient art of origami is being applied to fields such a robotics, medicine and space exploration. Wei-Haas notes that Prof. Daniela Rus and her team developed a robot that can fold to fit inside a pill capsule, while Prof. Erik Demaine has designed complex, curving fold patterns. “You get these really impressive 3D forms with very simple creasing,” says Demaine.

Researchers from MIT and Harvard have developed “a new type of electrically conductive hydrogel ‘scaffold’ that could eventually be used to create a soft brain-computer interface (or BCI) that translates neural signals from the brain into machine-readable instructions,” reports Adam Bluestein for Fast Company.

Prof. Evelina Fedorenko speaks with Atlantic reporter Matteo Wong about her research exploring how “the brain behaves when an individual speaks different languages.” Fedorenko explains that “it seems like languages provide us with mappings between forms and meanings.”

Researchers at MIT have found that those with an E4 variant display abnormalities in cholesterol metabolism, reports William A. Haseltine for Forbes. “The MIT team suggest that the disruption of cholesterol metabolism could be a fundamental reason why those with the E4 variant are more likely to develop Alzheimer’s disease symptoms,” writes Haseltine.

MIT scientists have found that silent synapses - a type of memory-forming synapse - are present in the adult brain, reports The Economist. The discovery of these silent synapses, explains Prof. Mark Harnett, “is a lever for us to get into understanding learning in adults and how potentially we can get access to make it not degrade over the course of aging or disease.”

Research affiliate Ramin Hasani speaks with Kimberly Adams of Marketplace about how he and his CSAIL colleagues solved a differential equation dating back to the early 1900s, enabling researchers to create an AI algorithm that can learn on the spot and adapt to evolving patterns. The new algorithm “will enable larger-scale brain simulations,” Hasani explains.

The Atlantic highlights a section of Prof. Alan Lightman’s forthcoming book, “The Transcendent Brain: Spirituality in the Age of Science.” Lightman writes, “I call myself a spiritual materialist. As a scientist, I’m a materialist. Not in the sense of seeking happiness in cars and nice clothes, but in the literal sense of the word: the belief that everything is made out of atoms and molecules, and nothing more. Further, I believe that the material stuff of the universe is governed by a small number of fundamental laws. Yet I have had transcendent experiences.”

An MIT research study suggests that those with the E4 variant of the APOE gene are more likely to develop Alzheimer’s symptoms, reports William A. Haseltine for Forbes. The variant “disrupts how fat molecules are processed in the brain,” writes Haseltine. “It appears that the disruption of these fat molecules could be the fundamental reason why those that contain the E4 variant are more likely to develop Alzheimer’s symptoms.”

Writing for NBC Boston 10, Senior Lecturer Tara Swart highlights three exercises that can help reduce stress and anxiety. “While anxiety can be scary, understanding how our bodies and brains react during those moments can remove some of the pressure and help us take control of our nervous system," writes Swart,

Researchers at MIT have found “the brain is not wired to transmit a sharp ‘stop’ command in the most direct or intuitive way,” reports Kevin Hartnett for Quanta Magazine. The brain “employs a more complicated signaling system based on principles of calculus,” writes Hartnett.