Neuroscience

Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li Huei Tsai, has developed a “specialized headset that delivers 40Hz auditory and visual stimulation” to the brain, which could potentially slow down the cognitive decline and neurodegeneration in Alzheimer’s disease, reports William A. Haseltine for Forbes. Prof. Li-Huei Tsai “and her team speculated that if gamma wave activity is reduced in Alzheimer’s disease, perhaps, artificially stimulating the brain may enhance synchronized firing and restore cognition,” writes Haseltine.

Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li-Huei Tsai, is using a 40 Hzlight-flickering and auditory headset to help slow the progression of Alzheimer’s and restore cognition, reports William A. Haseltine for Forbes. “A recent pilot clinical trial found that this technology is not only safe and tolerable for home use, but also has a positive impact on reducing symptoms associated with age-related neurodegeneration,” writes Haseltine.

Sloan Senior Lecturer Tara Swart Bieber speaks with Newsweek reporter Pandora Dewan about exercises that can help improve memory. "Memory is something that can be trained using neuroplasticity, which is the brain's ability to be malleable throughout life," said Bieber.

Forbes reporter Rob Toews spotlights Prof. Daniela Rus, director of CSAIL, and research affiliate Ramin Hasani and their work with liquid neural networks. “The ‘liquid’ in the name refers to the fact that the model’s weights are probabilistic rather than constant, allowing them to vary fluidly depending on the inputs the model is exposed to,” writes Toews.

Adjunct Prof. Tali Sharot speaks with NPR Life Kit host Marielle Segarra about how lying impacts the brain. Sharot refers to an experiment she conducted that used brain imaging technology to monitor how the brain reacts to lying and found that as adults “grew more comfortable lying, the emotional response decreased – meaning that the players became more and more desensitized to their dishonesty with each subsequent lie.”

MIT scientists have developed a new brain “atlas” and computer model that sheds insight into the brain-body connections in C. elegans worms, reports Lauren Leffer for Scientific American. “Through establishing those brain-behavior links in a humble roundworm,” writes Leffer, “neuroscientists are one step closer to understanding how all sorts of animal brains, even potentially human ones, encode action.”

Researchers from MIT and Harvard have explored astrocytes, a group of brain cells, from a computational perspective and developed a mathematical model that shows how they can be used to build a biological transformer, reports Kyle Wiggers for TechCrunch. “The brain is far superior to even the best artificial neural networks that we have developed, but we don’t really know exactly how the brain works,” says research staff member Dmitry Krotov. “There is scientific value in thinking about connections between biological hardware and large-scale artificial intelligence networks. This is neuroscience for AI and AI for neuroscience.

Prof. Ev Fedorenko has been studying the differences in “the neural architecture of speakers who speak languages with different properties,” reports Sofia Quaglia for Wired. “Her studies suggest that the core features of language systems in the brain seem similar across the board,” explains Quaglia.

The Economist spotlights several MIT studies that use artificial neural networks (ANN) to examine the human brain, including work by former postdoctoral researcher Daniel Yamins and his colleagues training ANNs to pick out objects from photographs, reports The Economist.

Writing for NBC Boston, Senior Lecturer Tara Swart shares various techniques that could help improve memory skills. “What separates people with excellent memory skills apart from those who struggle is that they have both a strong working memory (retaining information immediately after learning it) and long-term memory (recalling information more than a day after memorizing it,” writes Swart.

Popular Science reporter Jamie Dickman writes that using liquid neural networks, MIT researchers have “trained a drone to identify and navigate toward objects in varying environments.” Dickman notes that: “These robust networks enable the drone to adapt in real-time, even after initial training, allowing it to identify a target object despite changes in their environment.”

Researchers at MIT have developed a new type of autonomous drone that uses advanced neural networks to fly, reports Tony Ho Tran for The Daily Beast. “The new design allows the drone to make better decisions when flying through completely new environments,” writes Tran, “and could have future applications in self-driving cars, search and rescue operations, wildlife monitoring, or even diagnosing medical issues.”

Prof. Li-Huei Tsai and Prof. Ed Boyden co-founded Cognito Therapeutics after their research found that gamma waves could help clear amyloid plaques, which are known to appear in Alzheimer’s patients, reports Ryan Cross for The Boston Globe.  “It was the most surprising result I’ve ever got in my life,” says Tsai. “When we published our first paper, most people said, ‘I don’t believe it. This is too good to be true. How can something this simple have this kind of effect?’”

In an excerpt from “Your Brain on Art” published in Fast Company, Susan Magsamen and Ivy Ross spotlight Prof. Li-Huei Tsai research exploring whether gamma oscillations from light and sound could help ease Alzheimer’s symptoms. “Li-Huei believes that increased gamma oscillations in the brain engage many different systems and cell types,” write Magsamen and Ross. “Because of this, the gamma waves may help with amyloid removal.”

Prof. Josh McDermott co-authored a study that explores how music and podcasts can impact a person’s mood, reports Charlotte Hu for Popular Science. “There’s this big cultural shift in the way that we consume music and other audio that really happened over the last decade,” says McDermott. “It’s just changed the way that people live and probably has a lot of important effects.”