Scientists pinpoint where thousands of individual proteins are made in intact tissue and single cells
A new technology called RIBOmap can give researchers valuable insight into how protein production in animal and human tissue is altered in disease.
Without a key extracellular protein, neuronal axons break and synaptic connections fall apart
Scientists find a protein common to flies and people is essential for supporting the structure of axons that neurons project to make circuit connections.
Astrocyte cells critical for learning skilled movements
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.
A “golden era” to study the brain
“We can’t think of the brain only as neurons,” says PhD student Mitch Murdock, who explores the cellular basis of Alzheimer’s disease.
Study reveals how environment and state are integrated to control behavior
A simple animal model shows how stimuli and states such as smells, stressors, and satiety converge in an olfactory neuron to guide food-seeking behavior.
When Alzheimer’s degrades cells that cross hemispheres, visual memory suffers
Research reveals cells that span brain hemispheres to coordinate activity in visual processing centers, shows Alzheimer’s degrades their structure and function.
Circuit that focuses attention brings in wide array of inputs
With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function.
Memory-making involves extensive DNA breaking
To quickly express learning and memory genes, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows.
Seemingly similar, two neurons show distinct styles as they interact with the same muscle partner
Diversity in how cells talk to the muscle they innervate reveal distinct propensities for change, or “plasticity.”
What separates the strong from weak among connections in the brain
MIT study finds synapses develop strength with calcium, maturation.
Picower study finds connection between rare muscle disease and autoimmune disorders
Patients with a rare neuromuscular disorder and those with nerve damage tied to autoimmune disorders may share the same faulty synapses.
Seeking a ‘parts list’ for the retina
New technique classifies retinal neurons into 15 categories, including some previously unknown types.
Researchers develop new method to control nanoscale diamond sensors
Technique allows tiny sensors to monitor small changes in magnetic fields, such as when neurons transmit electrical signals.
DNA damage may cause ALS
New study finds link between neurons’ inability to repair DNA and neurodegeneration.