Medicine

Newsweek reporter Pandora Dewan spotlights MIT researchers and their work developing an ingestible vibrating pill that can mimic the sensation of fullness. "The development of new non-invasive methods for treating obesity is of importance in confronting the multifaceted challenges posed by this global health crisis," says Shriya Srinivasan PhD ’20. "Traditional interventions, such as invasive surgeries, can be associated with significant risks, costs and lifestyle modifications, limiting their applicability and effectiveness.”

Researchers at MIT have developed a vibrating pill that can be swallowed before eating to create a feeling of fullness, reports Nicola Davis for The Guardian. “This approach offers an alternative and potentially synergistic approach to other therapies available today,” says Prof.  Giovanni Traverso.

Researchers at MIT have developed “a battery-operated capsule-like device that’s supposed to make you feel full by stretching out your stomach using vibration,” reports Miriam Fauzia for Inverse. “Considering that diet and exercise are hard to maintain, especially for long-term weight loss, and medical interventions like gastric bypass surgery and the newest wave of injectables cost more than a pretty penny, [Shriya] Srinivasan PhD ’20 and her colleagues want their vibrating pill to be an accessible alternative,” writes Fauzia.

Writing for Fast Company, Lecturer Guadalupe Hayes-Mota '08, SM '16, MBA '16 shares three strategies that are reshaping access to healthcare and medicine, especially in low-and middle-income countries (LMICs). “Integrating local production enhancement, strategic partnership and pooled purchasing power represents a new dawn in global health care,” writes Hayes-Mota. “These innovative approaches are pivotal in making quality medicine and healthcare accessible to all, particularly LMICs.”

Researchers from MIT have developed, “nanoelectronics they hope can one day enter the brain and treat conditions like Alzheimer’s by monitoring some of these brain patterns,” reports Elizabeth Hlavinka for Salon. “Their device, which they call Cell Rover, serves as a sort of antenna that can help external devices monitor cells.”

Forbes contributor William Haseltine spotlights how MIT researchers developed a biosensor ingestible capsule that can gather and transmit information on a patient’s condition to a physician. Haseltine notes that “aside from respiratory and heart rate monitoring, future applications for the pill could come from alterations in its design, leading to other avenues of health monitoring. These may include digestive health, blood sugar monitoring and cancer cell detection.” 

Lecturer Guadalupe Hayes-Mota '08, SM '16, MBA '16 writes for the National Academy of Engineering to discuss the importance of a “well-functioning healthcare supply chain.” “A connected supply chain represents a paradigm shift, offering the potential to revolutionize how drugs are developed, produced, and delivered to patients,” writes Hayes-Mota. “Embracing this approach can enhance drug delivery efficiency, ensure patient satisfaction, and ultimately contribute to a healthier and more prosperous global community.”

Forbes contributor William Haseltine spotlights how MIT researchers have developed a flexible ultrasound patch that can be used to help estimate bladder volume. “The applications for long-term therapeutic and regenerative medicine for the ultrasound patch are innumerable, only to be limited by the imagination of those implementing their use,” writes Haseltine. “Among the most forthcoming are situations where someone may be unable to visit their physician for a medically-administered ultrasound.”

Researchers from MIT and elsewhere are developing an electronic pill that can “measure heart rate, breathing rate and core temperature – from inside a human stomach,” reports Celia Ford for Wired. “We have a solution that’s relatively simple and enables access broadly,” says Prof. Giovanni. “I think that can be really transformative.”

Researchers from MIT and elsewhere have developed a swallowable “technopill” that can monitor vital signs from inside the body, reports Dennis Thompson for HealthDay. “The ability to facilitate diagnosis and monitor many conditions without having to go into a hospital can provide patients with easier access to healthcare and support treatment,” says Prof. Giovanni Traverso.

Prof. Gio Traverso speaks with Lizzy Lawler at STAT about a new ingestible sensor that monitors a person’s heart and breathing rates to detect sleep disorders. “The vision for sleep evaluation is the ability to detect these events wherever you are in the nation, and not having to go to a sleep lab and an inpatient setting,” says Traverso.

New Scientist reporter Alice Klein writes that MIT researchers have developed an ingestible electronic device that “can measure your breathing and heart rate from inside your gut [and] could potentially diagnose sleep apnea and even detect opioid overdoses.” The device could one day allow “people to be assessed for sleep apnea wirelessly and cheaply while at home.”

Researchers at MIT and elsewhere have developed a new type of cancer treatment – a gel that can be used to deliver cancer drugs for solid tumors, reports WHDH. “It’s really transformative to try and help patients whose tumors are very resistant to therapy,” says Prof. Giovanni Traverso.

Researchers at MIT and elsewhere have developed a swallowable electronic capsule that can be used to help diagnose sleep apnea and other sleep disorders, reports Ian Randall for Newsweek. “Conventional laboratory and home sleep studies require the patient to be attached to many different sensors,” says Prof. Giovanni Traverso. “As you can imagine, trying to sleep with all of this machinery can be challenging. [The] ingestible capsule just requires that the patient swallow the vitamin-sized pill. It's easy and unobtrusive and can accurately measure both respiratory rate and heart rate while the patient sleeps."

Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li Huei Tsai, has developed a “specialized headset that delivers 40Hz auditory and visual stimulation” to the brain, which could potentially slow down the cognitive decline and neurodegeneration in Alzheimer’s disease, reports William A. Haseltine for Forbes. Prof. Li-Huei Tsai “and her team speculated that if gamma wave activity is reduced in Alzheimer’s disease, perhaps, artificially stimulating the brain may enhance synchronized firing and restore cognition,” writes Haseltine.