A team of scientists, including researchers at MIT, are attempting to treat gastrointestinal disorders by using a foam that delivers low-levels of carbon monoxide to the body, reports Akila Muthukumar for STAT. “Every therapeutic, including food or water, is toxic when taken at certain levels,” said Prof. Gio Traverso. “It’s important to recognize that when delivered or administered appropriately, things can also have benefits.”
Using techniques from molecular gastronomy, Prof. Giovanni Traverso and his colleagues have created a carbon monoxide foam that may be able to treat gastrointestinal disorders by delivering low-levels of the gas to the body, reports Grace Wade for New Scientist. “I don’t know if there is another foam out there used to deliver therapeutic gases,” says Traverso. “This opens up a whole new way of how we think about therapeutics.”
A study co-authored by MIT researchers finds that algorithms based on clinical medical notes can predict the self-identified race of a patient, reports Katie Palmer for STAT. “We’re not ready for AI — no sector really is ready for AI — until they’ve figured out that the computers are learning things that they’re not supposed to learn,” says Principal Research Scientist Leo Anthony Celi.
Scientists from MIT and Brigham and Women’s Hospital have developed a plant-based gel that can be used to deliver effective doses of antimicrobial drugs around the world, reports Ed Cara for Gizmodo. The gels “can be produced cheaply and combined with edible materials like beeswax to create different textures and viscosity, ranging from something like a protein shake to yogurt,” writes Cara.
Researchers at MIT worked with colleagues at Brigham and Women’s Hospital to develop a gel that could deliver drugs that typically come in pill form. “The work involved testing gel formulations with trained food tasters who found that the most appealing versions were made from cottonseed oil (neutral flavor) or sesame oil (nutty flavor),” reports Amanda Kooser for CNET.
New York Times columnist Peter Coy spotlights the research of Prof. Nancy Leveson and Elizabeth White Baker SM ‘22 examining how to detect and prevent errors in the administration of medication. Baker noted that her research at MIT taught her that “hospital administrators sometimes try to save money by stinting on safety measures even though improving safety is cheaper in the long run because it helps saves on costs like defending against malpractice lawsuits.”
FiercePharma’s Nick Paul Taylor writes about a new drug delivery gel developed by researchers at MIT and Brigham and Women’s Hospital. “Our system is an oil-based system gel, which makes it compatible with most drugs,” says visiting scientist Ameya Kirtane. “This enables the formulation of drugs that were not available in semi-solid or liquid dosage forms and allows patients, especially children, to more easily take their medicine.”
MIT researchers have developed a new drug-delivering gel that could make it easier for children and adults to swallow their medicine, reports Gwen Egan for Boston.com. The gel could be made in a variety of different textures and can be stored without refrigeration.
Researchers from MIT and Brigham and Women’s Hospital have developed a gel that can be mixed into medicine to make it easier to swallow, reports CBS Boston. “The gel is made out of plant-based oils and doesn’t have to be refrigerated,” says CBS Boston. “The hope is that it can one day be used to help children and adults who have trouble swallowing pills.”
InsideTracker - a personalized-nutrition company founded by scientists from MIT, Harvard, and Tufts University - utilizes blood tests to calculate biological age, reports Betsy Morris for The Wall Street Journal. The company analyzes blood samples for “markers of conditions like inflammation, heart health and liver or kidney disorder,” explains Morris. “Those who test as older than their years get recommendations to adjust diet, exercise and supplements.”
Researchers at MIT and Harvard Medical School have created an artificial intelligence program that can accurately identify a patient’s race based off medical images, reports Tony Ho Tran for The Daily Beast. “The reason we decided to release this paper is to draw attention to the importance of evaluating, auditing, and regulating medical AI,” explains Principal Research Scientist Leo Anthony Celi.
During the AI Cures Conference, Prof. Regina Barzilay spoke with Food and Drug Administration senior staff fellow Amir Khan about how the agency intends to regulate artificial intelligence in medicine, reports Casey Ross for STAT. “’My thinking is that models should be regulated based on their functionality, and not necessarily on the input data they use,” said Barzilay.
J-PAL research manager Jesse Gubb writes for STAT about how voluntary innovation tests can lead to providers favoring profitable programs over what is best for patients and can make potential reforms harder to evaluate. “The Center for Medicare and Medicaid Innovation is in the rare position of being empowered to develop innovative payment models and prospectively evaluate them,” writes Gubb. “Mandatory, national randomized evaluations ensure that the already significant effort to develop the models will yield the rigorous evidence needed to support decisions on whether to scale and adopt them broadly.”
STAT reporter Katie Palmer spotlights Principal Research Scientist Leo Anthony Celi’s research underscoring the importance of improving the diversity of datasets used to design and test clinical AI systems. “The biggest concern now is that the algorithms that we’re building are only going to benefit the population that’s contributing to the dataset,” says Celi. “And none of that will have any value to those who carry the biggest burden of disease in this country, or in the world.”
Boston Globe reporter Michael Blanding spotlights Prof. Hugh Herr’s work with Dr. Matthew Carty in developing a new amputation surgery called agonist-antagonist myoneural interface (AMI) procedure, which reconnects muscles to amplify electrical signals sent along the nerves. “My dream as a scientist is that a person with an arm amputation could play a Beethoven piece at normal speeds and dexterity – and for legs, that a person could dance ballet,” says Herr.