Koch Institute

The star-shaped drug delivery device, held here by Giovanni Traverso, a Koch Institute research affiliate, can be folded inward and encased in a smooth capsule. Once ingested, the device delivers a full drug payload gradually over weeks or even months.

New capsule achieves long-term drug delivery

Technology could aid in elimination of malaria and treatment of many other diseases.

November 16, 2016

David H. Koch Institute Professor Robert Langer speaks with MIT students as part of the "Failures in Graduate School" seminar series.

Robert Langer reflects on failure, resilience, and making an impact

Institute Professor and world-renowned engineer shares his experiences as an MIT grad student as part of the “Failures in Graduate School” series.

October 31, 2016

T cells — immune cells that are targeted to find and destroy a particular antigen — are key to the adaptive immune response. In this image, the top row shows few T cells in untreated mice, while the bottom rows show many T cells produced after immunotherapy treatment.

Fighting cancer with the power of immunity

New treatment elicits two-pronged immune response that destroys tumors in mice.

October 24, 2016

Paula Hammond, the David H. Koch Professor in Engineering and head of MIT’s Department of Chemical Engineering, has been elected to the National Academy of Medicine in recognition of her distinguished contributions to medicine and health.

Paula Hammond elected to the National Academy of Medicine

Chemical engineer recognized for her contributions to medicine and health.

October 17, 2016

Researchers have developed a novel way to test tumors for drug susceptibility. They successfully tested this approach with a very aggressive type of brain cancer called glioblastoma multiforme and a type of blood cancer, pictured here in dark purple, known as acute lymphoblastic leukemia.

A new strategy for choosing cancer drugs

Device can predict tumor responses by measuring cell growth after drug exposure.

October 10, 2016

Nanosensors could help determine tumors’ ability to remodel tissue

Measuring enzyme levels could help doctors select appropriate treatments.

September 29, 2016

Clockwise from top left: MIT professors Ed Boyden, Jacquin Niles, Feng Zhang, and Matthew Vander Heiden have been named HHMI Faculty Scholars.

Four MIT professors named inaugural Faculty Scholars

New program from the Howard Hughes Medical Institute, Simons Foundation, and Bill and Melinda Gates Foundation supports early-career scientists.

September 22, 2016

A team of MIT scientists has developed a strategy for delivering large numbers of beneficial bacterial to the human gut. The strategy involves coating bacteria with polymer layers that protect them from the acids and bile salts found in the digestive tract.

Delivering beneficial bacteria to the GI tract

Method that transports microbes through the stomach to the intestine may benefit human health.

September 14, 2016

A new technique invented at MIT can precisely measure the growth of many individual cells simultaneously. “The device provides new insights into how cells grow and respond to drugs,” MIT professor Scott Manalis says.

Microchip enables fast, precise measurement of single-cell growth

Device that measures growth of many individual cells simultaneously could lead to rapid tests for antibiotics.

September 5, 2016

MIT researchers have added an extra layer of control to the CRISPR gene-editing approach, by making the system responsive to light.

Using light to control genome editing

New technique offers precise manipulation of when and where genes are targeted.

August 25, 2016

In humans and most other organisms, a circadian clock governed by light regulates the timing of key aspects of human physiology, by controlling cellular activities such as metabolism and division.

Why working the night shift can pose a cancer risk

New study reveals a link between circadian clock disruption and tumor growth.

July 28, 2016

Researchers at MIT and the University of California at San Diego have delivered artificial genetic circuits into bacteria, allowing the microbes to kill cancer cells in three different ways. Here, an image of a motherboard has been micropatterned using programmable probiotic bacteria. The bright lines are composed of dots made of bacteria. This technique was developed in the lab of MIT professor S...

Cancer-fighting bacteria

Engineers program E. coli to destroy tumor cells.

July 20, 2016

Michael Mitchell has been recognized with a Burroughs Wellcome Fund Career Award at the Scientific Interface for his research on developing a new class of materials and devices that detect and treat bone marrow disorders.

Michael Mitchell wins Burroughs Wellcome Fund Career Award at the Scientific Interface

MIT postdoc is among 10 scientists honored for combining biology with the physical sciences and engineering toward medical breakthroughs.

July 5, 2016

“This nanoformulation approach allows us to make vaccines against new diseases in only seven days, allowing the potential to deal with sudden outbreaks or make rapid modifications and improvements,” says Daniel Anderson, an associate professor in MIT’s Department of Chemical Engineering and a member of MIT’s Koch Institute for Integrative Cancer Research and Institute for Medical Engineeri...

Engineers design programmable RNA vaccines

Tests in mice show the vaccines work against Ebola, influenza, and a common parasite.

July 4, 2016

A new report, “Convergence: The Future of Health,” draws on insights from scientists and researchers across academia, industry, and government. The cover of the report is an image of lungs, one of the major sites of metastasis. To help protect the lungs (blue) from this deadly process, bioengineers have created microscopic drug depots (red) to focus the effect of anti-cancer drugs that may hav...

A strategy for “convergence” research to transform biomedicine

Report calls for more integration of physical, life sciences for needed advances in biomedical research.

June 23, 2016

MIT News | Massachusetts Institute of Technology

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