Institute for Medical Engineering and Science (IMES)

"From Controversy to Cure: Inside the Cambridge Biotech Boom" documents how science, engineering, politics, the space race, and urban renewal transformed a desolate Kendall Square into the biotechnology hub we recognize today. At left is the undeveloped plot that is now home to Draper Laboratory, as seen from what is now Galileo Way, looking west, with 400 Technology Square at far left.

“From Controversy to Cure” documentary chronicles the biotech boom in Cambridge, Massachusetts

Film looks at how Kendall Square became a beacon for industries working on treatments for diseases like cancer, Alzheimer’s, and diabetes.

November 20, 2019

MIT researchers have developed a method to isolate T cells that bind to different targets and then sequence their RNA.

Technique identifies T cells primed for certain allergies or infections

Researchers develop a method to isolate and sequence the RNA of T cells that react to a specific target.

November 19, 2019

MIT engineers created clusters of nanoparticles that are coated with “right-handed” molecules of the amino acid cysteine.

Nanoparticle orientation offers a way to enhance drug delivery

Coating particles with “right-handed” molecules could help them penetrate cancer cells more easily.

November 5, 2019

MIT engineers have devised a double-sided adhesive that can be used to seal tissues together.

Double-sided tape for tissues could replace surgical sutures

New adhesive that binds wet surfaces within seconds could be used to heal wounds or implant medical devices.

October 30, 2019

MIT professors Richard Young (left) and Sangeeta Bhatia

Two from MIT elected to the National Academy of Medicine for 2019

Sangeeta Bhatia and Richard Young recognized for their contributions to “advancement of the medical sciences, health care, and public health.”

October 21, 2019

A white-stained cluster of amyloid plaque proteins, a hallmark of Alzheimer's disease pathology, is evident in the mammillary body of a 2-month-old Alzheimer's model mouse. A new study finds that plaques begin in such deep regions and spread throughout the brain along specific circuits.

Alzheimer’s plaque emerges early and deep in the brain

Clumps of amyloid protein emerge early in deep regions, such as the mammillary body, and march outward in the brain along specific circuits.

October 8, 2019

MIT chemical engineers have developed a new series of lipid nanoparticles to deliver RNA vaccines.

Delivery system can make RNA vaccines more powerful

Vaccines packaged in novel nanoparticles could offer a new way to fight cancer and infectious diseases.

September 30, 2019

Depiction of a soft robotic device known as a dynamic soft reservoir (DSR)

Soft robotics breakthrough manages immune response for implanted devices

Discovery could enable longer-lasting and better-functioning devices — including pacemakers, breast implants, biosensors, and drug delivery devices.

September 4, 2019

MIT and Boston Children’s Hospital researchers have devised a minimally invasive way to monitor intracranial pressure in patients suffering from traumatic brain injuries or infectious diseases. Current techniques for measuring pressure within the brain are so invasive that the measurement is only performed in high-risk patients.

A much less invasive way to monitor pressure in the brain

New technique could help doctors determine whether patients are at risk from elevated pressure.

August 23, 2019

MIT engineers created a DNA-acrylamide gel that can be degraded by DNA-editing enzymes. At right, the gel is broken down after two hours of exposure to a DNA "trigger sequence." At left, the gel is exposed to DNA that doesn't contain the trigger sequence, so it remains intact.

Using CRISPR to program gels with new functions

Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.

August 22, 2019

Yearlong hackathon engages nano community around health issues

Hacking Nanomedicine kicks off a series of events to develop an idea over time.

August 9, 2019

MIT researchers have developed a new model of gene control, in which the cellular machinery that transcribes DNA into RNA forms specialized droplets called condensates.

Study furthers radically new view of gene control

Along the genome, proteins form liquid-like droplets that appear to boost the expression of particular genes.

August 8, 2019

Jaume Plensa sculpture, "The Alchemist" on MIT's campus

School of Engineering second quarter 2019 awards

Faculty members recognized for excellence via a diverse array of honors, grants, and prizes over the past quarter.

July 30, 2019

A course called Machine Learning for Healthcare introduces students to the technical and ethical challenges of using automated tools to diagnose and treat patients.

Want to know what software-driven health care looks like? This class offers some clues.

A course that combines machine learning and health care explores the promise of applying artificial intelligence to medicine.

July 24, 2019

MIT engineers have devised a way to incorporate crystallized immunosuppressant drugs into devices carrying encapsulated islet cells, which could allow them to be implanted as a long-term treatment for diabetes.

A better way to encapsulate islet cells for diabetes treatment

Crystallized drug prevents immune system rejection of transplanted pancreatic islet cells.

June 24, 2019

MIT News | Massachusetts Institute of Technology

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