Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.
Seed projects, posters represent a wide range of labs working on technologies, therapeutic strategies, and fundamental research to advance understanding of age-related neurodegenerative disease.
At an exhibition marking two decades since a transformative gift from the Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond.
Graybiel lab identifies genes linked to abnormal repetitive behaviors often seen in models of addiction and schizophrenia.
A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.
Two MIT faculty members earn funding from the G. Harold and Leila Y. Mathers Foundation.
Opioid receptor MOR1 changes discovered in neurodegenerative disease model.
Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.
Gifts to MIT and Harvard Medical School totaling $9 million will fund independent research on cannabinoid’s influence on brain health and behavior.
Yeast protein could offer clues to how Alzheimer’s plaques form in the brain.
Newly tenured biological engineer Ernest Fraenkel goes where the numbers lead.
Mutant forms of the gene disrupt chemical modifications that control access to genes necessary for normal brain cell function.
Discovery could lead to new drugs to fight Alzheimer’s and other neurological diseases.