New gene-editing system precisely inserts large DNA sequences into cellular DNA
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
Scientists engineer new CRISPR platform for DNA targeting
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.
New CRISPR tool opens up more of the genome for editing
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
Researchers advance CRISPR-based tool for diagnosing disease
With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.
Reading and writing DNA
Department of Biology kicks off IAP seminar series with a lecture by synthetic-biology visionary George Church.
Researchers engineer CRISPR to edit single RNA letters in human cells
“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.
Gene-editing technology developer Feng Zhang awarded $500,000 Lemelson-MIT Prize
MIT associate professor and member of the Broad Institute and McGovern Institute recognized for commitment to invention, collaboration, and mentorship.
Feng Zhang to share Albany Medical Prize
Five recipients honored for their fundamental and complementary accomplishments related to CRISPR-Cas9.
Scientists unveil CRISPR-based diagnostic platform
New system adapts tool known for gene editing; to be used in rapid, inexpensive disease diagnosis.
3Q: Behind the scenes of the National Academy of Sciences' report on human genome editing
MIT professor and NAS report committee co-chair Richard Hynes gives insight into the report’s recommendations.
Feng Zhang named a runner-up for TIME’s 2016 Person of the Year
MIT and Broad Institute scientist shares recognition with four other scientists for developing CRISPR gene-editing systems.
Targeting genes by the thousands
PhD student Tim Wang uses CRISPR to take a big-picture approach to cancer research.
Feng Zhang named 2016 Tang Prize laureate
Broad Institute/MIT scientist among three honored for CRISPR contributions.
New CRISPR system for targeting RNA
Scientists program C2c2, discovered in bacteria as a viral defense mechanism, to manipulate cellular RNA.
Feng Zhang receives 2016 Canada Gairdner International Award
Broad/MIT scientist among five honored as pioneers of CRISPR-Cas9 system.