Using plant biology to address climate change
A Climate Grand Challenges flagship project aims to reduce agriculture-driven emissions while making food crop plants heartier and more nutritious.
Volta Labs: Improving workflows for genetic applications
Udayan Umapathi SM ’17 and Will Langford SM ’14, PhD ’19 are co-founders of a Media Lab spinoff building a full-stack platform to enable automation for genomics and genetic engineering.
RNA-targeting enzyme expands the CRISPR toolkit
Exploring diversity among bacterial immune systems, McGovern Institute scientists uncovere a programmable system for precisely targeting and modifying RNA.
New programmable gene editing proteins found outside of CRISPR systems
Researchers find RNA-guided enzymes are more diverse and widespread than previously believed.
Scientists harness human protein to deliver molecular medicines to cells
Made of components found in the human body, the programmable system is a step toward safer, targeted delivery of gene editing and other molecular therapeutics.
A new technique for correcting disease-causing mutations
Novel method, developed by McGovern Institute researchers, may lead to safer, more efficient gene therapies.
An on-off switch for gene editing
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.
New molecular therapeutics center established at MIT's McGovern Institute
Collaborative research center funded by Lisa Yang and Hock Tan ’75 blends engineering and neuroscience to advance molecular tools for treating brain disorders.
Nature-inspired CRISPR enzymes for expansive genome editing
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
Making real a biotechnology dream: nitrogen-fixing cereal crops
Voigt Lab's work could eventually replace cereal crops’ need for nitrogen from chemical fertilizers.
Using gene editing, neuroscientists develop a new model for autism
By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.
New gene-editing system precisely inserts large DNA sequences into cellular DNA
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
Biotech startup uses nanoparticles to induce immune tolerance
Selecta Bioscience’s ImmTOR platform could improve gene therapies and prevent some drug side effects.
Keeping genetic engineering localized
Researchers are developing a so-called "daisy-chain" gene-drive system that provides controls for genetic engineering of certain populations.
Scientists engineer new CRISPR platform for DNA targeting
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.