Scientists identify mechanism behind drug resistance in malaria parasite
SMART researchers find a cellular process called transfer ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance.
Using AI, MIT researchers identify a new class of antibiotic candidates
These compounds can kill methicillin-resistant Staphylococcus aureus (MRSA), a bacterium that causes deadly infections.
A novel combination therapy counters antibiotic-resistant Mycobacterium abscessus infections
SMART researchers combine rifaximin and clarithromycin to effectively restore the latter drug's efficacy.
Using AI, scientists find a drug that could combat drug-resistant infections
The machine-learning algorithm identified a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings.
SMART researchers discover unique lysin capable of killing multidrug-resistant bacteria
Novel lysin Abp013 has shown promising antimicrobial ability against Acinetobacter baumannii and Klebsiella pneumoniae.
Drug makes tumors more susceptible to chemo
Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.
Painting a fuller picture of how antibiotics act
Machine learning reveals metabolic pathways disrupted by the drugs, offering new targets to combat resistance.
Fine-tuning cancer medicine
New cancer research initiative eyes individualized treatment for patients.
James Collins appointed 2016 Allen Distinguished Investigator
Award will support the engineering of safe, frequently consumed bacteria to detect and kill dangerous bacteria such as those causing drug-resistant infections.
Resistance is futile
Chemists develop new way to kill cancer cells resistant to the chemotherapy drug cisplatin.