MIT researchers have developed a new drug delivery capsule that can deliver medication over extended periods of time, reports Claire Maldarelli for Popular Science. Once in the stomach, the capsule opens into a star shape, which “prevents the pill from leaving the stomach and entering the small intestine.”
Researchers at MIT have developed a slow-release drug capsule that can last two weeks in a person’s stomach, writes Jamie Ducharme for Boston Magazine. “The capsule was tested for use in malaria prevention, but the researchers behind it say it could be used for virtually any condition that requires regular oral medication,” Ducharme explains.
Reuters reporter Kate Kelland writes that MIT researchers have created a new drug-delivery capsule that can stay in the stomach for up to two weeks after being swallowed. The star-shaped device could be “a powerful weapon in fighting malaria, HIV and other diseases where successful treatment depends on repeated doses of medicine.”
MIT researchers have developed a star-shaped, drug-delivery device that can stay in the stomach for up to two weeks, gradually releasing medication, reports Melissa Healy for The Los Angeles Times. The researchers believe the device could be useful in “delivering a wide range of medications for diseases in which patient non-adherence is a problem.”
MIT researchers have developed a stretchy, biocompatible material that could be implanted in a patient’s body and used to stimulate cells or detect disease, according to FOX News. The hydrogel “could bend and twist in a patient’s body without breaking down.”
MIT researchers have developed a new technique to stop the spread of cancer cells through the body by delivering microRNAs to the site of the primary tumor, reports Hallie Smith for Boston Magazine. The technique “may correct gene disruptions that put a patient at risk of metastatic cancer,” Smith explains.
In a Huffington Post video, Prof. Daniela Rus explains that the ingestible origami robot her team developed could enable incisionless surgery. “What we have developed so far is a proof of concept that shows that you could have tetherless machines that can do active and important functions inside the body,” she explains.
Popular Science reporter Sarah Chodosh writes that MIT researchers have developed a strategy to deliver beneficial bacteria to the GI tract. The researchers used layers of different sugars "to coat individual cells of Bacillus coagulans, which is used to treat irritable bowel syndrome."
Prof. Robert Langer talks to Jessica Harris from NPR about his research on tissue engineering and drug delivery, the commercialization of his discoveries, and the many companies he has started. Langer says he started his lab based off his desire to improve people’s lives by conducting research “at the interface of chemical engineering and medicine.”
Edd Gent writes for LiveScience that MIT researchers “have devised a new fabrication process that uses ultraviolet (UV) light to print successive layers of polymers into 3D, Transformer-like structures that ‘remember’ their shapes.”
MIT researchers have developed a method to 3-D print heat-responsive materials that can remember their original form, reports Rachel Zimmerman for WBUR. Prof. Nicholas Fang explains that this development is "critical for drug delivery — you could deliver a smaller, more tailored dose depending on the temperature change."
Salon reporter Scott Eric Kaufman writes that MIT researchers are using light to print 3-D structures that are able to remember their original shapes, and could be used in solar panel tracking and drug delivery. Kaufman writes that the structures are capable “of springing back to their original forms.”
In a Scientific American article about polymers, Mark Peplow writes about Prof. Jeremiah Johnson’s research on how polymers could be used in drug delivery. “Sequence-controlled polymer could provide a more predictable biological effect, because every strand would be the same length and shape, and its chemistry could be carefully designed to assist its drug cargo,” writes Peplow.
Olga Kharif from Bloomberg Businessweek provides an overview of the origami robot created by Prof. Daniela Rus and her team. “Squeezed into a pill, this robot unfolds like an origami after it’s swallowed. It can be guided with a tiny magnet to remove a foreign object from the stomach or treat a wound by administering medication,” explains Kharif.
The Economist reports that Prof. Daniela Rus and Dr. Shuhei Miyashita have developed a tiny origami robot that can be swallowed and used to collect dangerous items that have been accidentally ingested. “The device is based on foldable robot technology that their team of researchers have been working on for years.”