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Drug delivery

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New Scientist

MIT researchers have developed a new way of creating drug-carrying particles that could allow multiple doses of a vaccine to be delivered over an extended period of time, reports Matt Reynolds for New Scientist. “The technology could eventually be used to create ‘omni-vaccines’ that protect against a whole host of diseases in one shot.”

Boston Magazine

Boston Magazine reporter Rowan Walrath writes that MIT researchers have developed a new technique that could be used to deliver multi-drug vaccines. The researchers developed a new method for “designing customizable, three-dimensional microparticles that resemble minuscule coffee cups. Each cup…contains a drug or vaccine ‘library’ that can be released at multiple points over an extended period of time.”

Boston Herald

Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a hydrogel-based capsule that can slowly release medications over several days and could help patients follow complex treatment regimens.  “A lot of people do not take their medication as prescribed,” explains postdoc Jinyao Liu. “With this, you just need a single dose.”

Inverse

Inverse reporter Dan Robitzski writes that MIT researchers have created a new gel-like coating that can be used to make medical devices feel more natural. The researchers, “developed the hydrogels to manufacture products that feel like the part of the body they contact — say, a catheter that feels like the inside of a urethra.”

Boston Magazine

Boston Magazine reporter Jamie Ducharme writes that MIT researchers have developed a new gel-like coating that can be used on medical devices like catheters and IV tubes to reduce friction and ease patient discomfort. The substance, “can be moved, stretched, and twisted without breaking, “Ducharme explains, and also, “acts as a lubricant for the objects it coats.”

BBC

Timandra Harkness of BBC Radio 4’s FutureProofing series spoke with research affiliate Gio Traverso and postdoc Phillip Nadeau about their ingestible electronic device that uses stomach acid to power tiny sensors. “Once you have the capacity to have a smart system sitting in your stomach that one can communicate with, it opens up the door to homing in on the individual patient,” said Traverso.

CBC News

Postdoctoral associate Phillip Nadeau speaks with CBC reporter Nora Young about a new ingestible electronic device developed by MIT researchers that could potentially be used to transmit patient data or deliver medications. Young explains that the new device “doesn't require a battery, because it's able to create an electrical current from the acid in your stomach.”

Science Friday

Research affiliate Giovanni Traverso speaks with Ira Flatow of Science Friday about a new ingestible device powered by stomach acid. “When you start thinking about keeping a system inside of the body for a long time,” Traverso explains, “powering that system becomes a challenge, and that’s exactly what we tried to aim to address here with this study.”

United Press International (UPI)

MIT researchers have developed an ingestible device that is powered by stomach acid and can deliver drugs for up to one week, reports Brooks Hays of UPI. "Our work helps pave the way toward a new era of pill-sized electronics, which can operate over the course of weeks or even months in the gastrointestinal tract,” says Giovanni Traverso, a research affiliate at the Koch Institute.

Boston Magazine

MIT researchers have developed a pill that uses stomach acid to run sensors in the body and can deliver drugs over a long period of time, writes Hallie Smith of Boston Magazine. By attaching zinc and copper electrodes to the exterior of the pill it “reacts with stomach acid to create electricity,” explains Smith.

Slate

MIT researchers have developed a new drug capsule that can deliver doses of medication over the course of several weeks, reports Robby Berman for Slate. Berman explains that the star-shaped device is like “a little pharmacy stationed in the stomach, ready to dispense doses at the desired times.”

Wired

Prof. Robert Langer speaks with Kathryn Nave of Wired about the future of drug delivery. Langer explains that a problem facing medical professionals is that many drugs are not taken regularly or as prescribed, and describes how he is developing a “long-acting pill that you could swallow to release the right drug dosage for weeks.”

WBUR

A new drug delivery system developed by MIT researchers may help eradicate malaria and could boost medication adherence, writes Rachel Zimmerman for WBUR’s Bostonomix. "People don't take their medicines and this might be a way, someday, for Alzheimer's patients to have much better treatments and people with mental health diseases to have much better treatments," says Prof. Langer.

Economist

MIT researchers have devised a capsule that can deliver medications over extended periods of time, and could be useful in halting the spread of malaria. The Economist notes that the device could be a “useful addition to the armory being deployed against malaria. And that, alone, could save many lives a year.”

STAT

Bob Tedeschi writes for STAT that MIT researchers have developed a device that can remain in the stomach for up to two weeks, gradually releasing medication. “The capsule represents the latest effort to solve a major flaw in drug delivery,” Tedeschi explains. “Because the human stomach clears its contents multiple times daily, pill takers must dose themselves frequently.”