MIT, Broad scientists overcome key CRISPR-Cas9 genome editing hurdle
Team re-engineers system to dramatically cut down on editing errors; improvements advance future human applications.
Mapping the 3-D structure of DNA
PhD student Abe Weintraub helps identify when DNA folding is helpful, and when it might cause cancer.
Biologists unravel drug-resistance mechanism in tumor cells
Targeting the RNA-binding protein that promotes resistance could lead to better cancer therapies.
Alumnus Paul Modrich wins Nobel Prize in chemistry
Biochemist who graduated from MIT in 1968 is honored for his work on DNA repair mechanisms.
Automating single-molecule image studies
MIT physics graduate student James Owen Andrews is developing software to improve dynamic image capture from super-resolution fluorescent microscopes.
Faculty Highlight: Ibrahim Cissé
Assistant professor of physics probes the formation of enzyme clusters that enable gene copying and protein production in living cells.
An ally for the understudied Y chromosome
Graduate student Alexander Godfrey tackles a chromosome that half the world has — yet few understand.
Pneumonia found to harm DNA in lung cells
Hydrogen peroxide produced by some bacteria causes DNA double-strand breaks, cell suicide.
DNA breakage underlies both learning, age-related damage
Process that allows brains to learn and remember also leads to degeneration with age.
Study details a link between inflammation and cancer
Timing of inflammation determines whether potentially cancerous mutations may arise.
Computer model enables design of complex DNA shapes
Engineers computer-design the most complicated 3-D structures ever made from DNA.
A double-edged sword
An enzyme key to DNA repair can worsen tissue damage caused by stroke and organ transplantation.
High-speed biologics screen
Engineers devise technology for rapidly testing drug-delivery vehicles in zebrafish.