Deciphering the cellular mechanisms behind ALS
Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.
A noninvasive treatment for “chemo brain”
Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.
What can super-healing species teach us about regeneration?
Albert Almada PhD ’13 studies the mechanics of how stem cells rebuild tissues. “Digging deep into the science is what MIT taught me,” he says.
A new test could predict how heart attack patients will respond to mechanical pumps
Performing this test could help doctors prevent dysfunction that can occur when the right and left ventricles of the heart become imbalanced.
Capsid of HIV-1 behaves like cell’s cargo receptor to enter the nucleus
Biologists demonstrate that HIV-1 capsid acts like a Trojan horse to pass viral cargo across the nuclear pore.
A new drug candidate can shrink kidney cysts
A compound originally developed to treat cancer could be repurposed to treat polycystic kidney disease, an inherited condition that can lead to kidney failure.
Turning history of science into a comic adventure
Associate Professor Lydia Bourouiba and artist Argha Manna take readers through a series of discoveries in infectious disease.
Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.
3 Questions: Darrell Irvine on making HIV vaccines more powerful
Human volunteers will soon begin receiving an HIV vaccine that contains an adjuvant developed in Irvine’s lab, which helps to boost B cell responses to the vaccine.
Aging Brain Initiative symposium showcases “cutting-edge” research across MIT
Seed projects, posters represent a wide range of labs working on technologies, therapeutic strategies, and fundamental research to advance understanding of age-related neurodegenerative disease.
Smart pill can track key biological markers in real-time
Coupling engineered bacteria with low-power electronics could be highly effective in diagnosis, treatment of bowel diseases.
How the body’s cells work together in response to infection
PhD student Constantine Tzouanas investigates how interactions between individual cells help determine whether pathogens will defeat their hosts — or vice versa.
A snapshot of cancer vaccine development
The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.
A cool path to disease deceleration
MIT PhD student Kathrin Kajderowicz is studying how hibernation-like states could pave the way for new hypothermic therapies.
Probe expands understanding of oral cavity homeostasis
A new approach opens the door to a greater understanding of protein-microbe interactions.