Activating a new understanding of gene regulation
Study reveals the role of the activation domain, a part of transcription factors previously shrouded in mystery.
Squeezing cells to cure diseases
Startup SQZ Biotech aims to open a new path in immunotherapy with its cell-compressing technique.
Testing new drugs with “ALS-on-a-chip”
3-D tissue model replicates the motor neuron connections affected by amyotrophic lateral sclerosis.
Scientists alter membrane proteins to make them easier to study
By making hydrophobic sections water-soluble, researchers hope to learn more about protein structures.
Charting a path to better cell models of the intestine
Researchers generate an intestinal cell mimic that can be harnessed in studies of diseases such as inflammatory bowel disease.
Structure of key growth regulator revealed
Researchers identify the molecular structure of the GATOR1 protein complex, which regulates growth signals in human cells, using cryo-electron microscopy.
Cholesterol helps flu virus escape through host cell’s membrane
Study could shed light on how many other proteins bind with membrane cholesterol.
Laura Kiessling wins Tetrahedron Prize for Creativity in Organic Chemistry
Professor of chemistry is the first woman to win the prestigious prize, awarded annually for creativity in organic chemistry or bioorganic and medicinal chemistry.
New faculty welcomed to Department of Biology
Assistant professors Joey Davis and Rebecca Lamason will spearhead research initiatives into fundamental cellular processes.
How cytoplasm “feels” to a cell’s components
In study that may guide drug design, researchers find organelles encounter varying levels of resistance.
Scientists program cells to remember and respond to series of stimuli
New approach to biological circuit design enables scientists to track cell histories.
How the spleen filters blood
Computer model finds slits in the spleen impose a “physical fitness test” on red blood cells.
New approach to sorting cells
Microfluidic device distinguishes cells based on how they respond to acoustic vibrations.
Spotting hidden activity in cells
New data analysis technique distinguishes active from passive fluctuations inside cells.
Piecing together molecular machines
Newly tenured biologist Iain Cheeseman explores the complex structures that control cell division.