SMART researchers develop 15-minute immune-profiling assay
Deterministic lateral displacement assay can rapidly assess host inflammatory response, identifying a potentially life-threatening hyper-aggressive immune response.
Membrane around tumors may be key to preventing metastasis
Tough as plastic wrap but elastic like a balloon, the lining could be a target for therapies to limit cancer cells from spreading.
Study reveals how egg cells get so big
Oocyte growth relies on physical phenomena that drive smaller cells to dump their contents into a larger cell.
Basic cell health systems wear down in Huntington’s disease, analysis shows
A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.
Metabolic mutations help bacteria resist drug treatment
Study suggests forcing bacteria to burn more energy could make them more susceptible to antibiotics.
3 Questions: Lindsay Case on how cells organize and sense the world
Case’s new lab investigates why cancer arises when disruptions in cellular organization change how cells sense mechanical forces.
Catching cancer in the act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.
Why cancer cells waste so much energy
MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.
“SCOUT” helps researchers find, quantify significant differences among organoids
Unbiased, high-throughput analysis pipeline improves utility of “minibrains” for understanding development and diseases such as Zika infection.
MIT launches Center for Multi-Cellular Engineered Living Systems
M-CELS are purpose-driven living systems with multiple interacting living components.
SMART researchers develop gelatin microcarrier for cell production
Gelatin-based microcarriers offer higher yield and scalability compared to existing commercial microcarriers.
Truncated immune system receptors may regulate cellular activity
Unexpected findings in chemokine receptors once believed to be non-functional open up new fields of scientific inquiry.
To make mini-organs grow faster, give them a squeeze
Study finds that compressing cells, and crowding their contents, can coax them to grow and divide.
Alzheimer’s risk gene disrupts endocytosis, but another disease-linked gene could help
Astrocytes with the APOE4 gene variant show deficits of a key cellular function, but overexpressing the gene PICALM overcame the defect.
SMART researchers receive Intra-CREATE grant for personalized medicine and cell therapy
Funds will support research on glaucoma through retinal biometrics and neural cell implantation therapy for spinal cord injury.