MIT researchers have developed a portable system that could produce biotech drugs on demand, reports Lisa Rapaport for Reuters. “The table-top machine has the potential to one day produce proteins to treat any number of a wide range of conditions like cancer, diabetes, heart attacks, and hemophilia,” writes Rapaport.
Prof. Susan Lindquist has been named a recipient of the Albany Medical Center Prize in Medicine and Biomedical Research, according to the AP. Lindquist’s research has raised hopes that “treatments could prevent protein ‘misfolding’ that drives degenerative conditions like Alzheimer's, Parkinson's and Lou Gehrig's disease.”
A portable device developed by MIT researchers uses programmable yeast to create drugs on demand, reports Jamie Ducharme for Boston Magazine. The device “could be a lifesaver for doctors working in vulnerable conditions, such as the battlefield, a remote village, or even an ambulance,” writes Ducharme.
MIT researchers have developed a programmable vaccine that could be used to respond to disease outbreaks, reports Ben Gruber for Reuters. The vaccine harnesses “messenger RNA, a genetic material that can be programmed to fight any viral, bacterial or parasitic disease by provoking an amplified immune response.”
Popular Science reporter Samantha Cole writes that MIT researchers have developed a laptop-sized, portable device that can produce biopharmaceuticals for doctors in remote locations. Cole explains that the device can “produce a single dose of treatment with a series of steps, using genetically engineered yeast cells as a mini 'factory' for a variety of customizable drugs.”
Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a portable pharmacy that can manufacture biopharmaceuticals and modify treatments. “Instead of relying on a cocktail that already exists, you can reprogram the reactor on demand to customize the treatment,” says Prof. Timothy Lu.
Prof. Linda Griffith speaks with Wired reporter Sarah Zhang about her work developing chips that can mimic human organs in an effort to better understand interactions between the immune system and the liver. Griffith is currently working to connect at least 10 miniature organs on a chip to study, for example, how breast cancer can spread to the liver.
MIT researchers have found that plants may use prions, the proteins responsible for mad cow disease, to form memories, reports Anil Ananthaswamy for New Scientist. “Prions, we think, are responsible for some really broad, really interesting biology,” says Prof. Susan Lindquist. “We have only seen the tip of the iceberg so far.”
Huffington Post reporter Carolyn Gregoire writes that MIT spinoff Synlogic is working on reprogramming gut bacteria to act as a living therapeutic. “It’s become really clear that the bacteria living in us and on us affect our bodies in a variety of different ways — in ways that we never imagined,” explains Prof. Timothy Lu.
STAT reporter Eric Boodman spotlights Prof. Jing-Ke Weng’s work searching for medical treatments in plants. Boodman writes that Weng is “determined to harness peanut skins, and twisted roots, and an herb known as horny goat weed...to treat human disease."
Washington Post reporter Laurie McGinley writes that Prof. Tyler Jacks, director of the Koch Institute for Integrative Cancer Research, was named to a panel of experts that will advise the Obama administration on the cancer “moonshot” initiative and how to best “tackle some of the most promising but challenging areas in research today.”
MIT researchers have found evidence that there may be windows of opportunity during which drugs are more effective at treating cancer, reports Ariana Eunjung Cha for The Washington Post. "If we know the route to resistance," explains Prof. Michael Hemann, "we can ambush tumor cells."
MIT researchers have uncovered a potential link between a high-fat diet and increased risk of many types of cancer, reports Chukwuma Muanya for The Guardian. Muanya explains that the study “reveals the effect that a high-fat diet has on the biology of stem cells… and how this might make cancer more likely.”
A new study by MIT researchers suggests that sea sponges may have been the first animal on Earth, CBS Boston reports. “Based on new genetic tests, researchers can say with confidence that molecules produced by sea sponges have been found in 640 million-year-old rocks.”
Prof. Michael Yaffe speaks with Scott Kirsner of WBUR’s Radio Boston about Vice President Joe Biden’s new cancer initiative. Prof. Yaffe says that the announcement comes at a “golden era for cancer research. We’ve laid the groundwork and we’re poised with incredible technologies, knowledge and understanding of the disease.”