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Biological engineering

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The Boston Globe

Boston Globe reporter Ryan Cross spotlights Chroma Medicine, a biotech startup co-founded by MIT researchers that is “developing a new class of gene editing technologies that could control how our genetic code is read without changing the code itself.” Cross explains that Chroma Medicine’s technology could “have broad applications for treating both rare and common diseases.”

Bloomberg

Bloomberg reporter Tanaz Meghjani writes that MIT researchers created a new system to 3D print a customized replica of the human heart, which could help improve replacement valve procedures. The new system “mimics blood flow and pressure in individual diseased hearts, suggesting a way to predict the effects of various replacements and select the best fit, avoiding potential leakage and failure,” Meghjani writes.

WBUR

MIT engineers have developed a new technique for 3D printing a soft, flexible, custom-designed replica of a patient’s heart, report Gabrielle Emanuel and Amy Sokolow for WBUR. The goal of the research is to “provide realistic models so that doctors, researchers and medical device manufacturers can use them in testing therapies for different types of heart disease,” Emanuel and Sokolow explain.

The Boston Globe

Aera Therapeutics, founded by Prof. Feng Zhang, is working to “debut a type of protein nanoparticle that it believes can be used to ferry all sorts of genetic medicines around the body,” reports Lisa Jarvis for Bloomberg.

The Boston Globe

Prof. Feng Zhang founded Aera Therapeutics, a startup working to deliver curative genetic medicine to hard-to-reach parts of the body, reports Ryan Cross for The Boston Globe. “If Aera’s approach works in people, it could broaden the reach of genetic therapies, which currently have limited clinical applications – partly because there aren’t enough methods for getting those medicines to hone in on the right cells,” writes Cross.  

The Boston Globe

Graduate student Karenna Groff ‘22 has been named NCAA Woman of the Year, an honor presented to a graduating female student-athlete who has distinguished herself in athletics, academics, leadership and community service, reports Matt Doherty for The Boston Globe. “I think the award is the first recognition I’ve gotten that looks into who I am and who I want to be,” says Groff. “I think it will help me frame the direction towards what I want the next chapter in my life to look like.”

CBS Boston

Graduate student Karenna Groff ’22 speaks with CBS Boston reporter Mike UVA about her academic and athletic accomplishments. “Groff become just the sixth Division III student-athlete ever to be recognized as the NCAA Woman of the Year,” says Uva. “An honor that celebrates excellence both on and off the field for all divisions.”

GBH

GBH reporter Esteban Bustillos spotlights graduate student Karenna Groff '22, the NCAA Woman of the Year, and her efforts to make a difference both on and off the field, from her work as an EMT at MIT to her efforts to reduce maternal mortality in southern India. “Using sports as a platform to drive forward equity in all these different walks of life has always been something that I want to be a part of,” explains Groff. 

Forbes

Asimov - an MIT spinout co-founded by Prof. Christopher Voigt, Alec Nielsen PhD ’16, Raja Srinivas PhD ’16, and Boston University Prof. Douglas Densmore - is a biotechnology company developing tools to design living systems, reports John Cumbers for Forbes. “Every cell is capable of computing. Perceiving environmental signals, information processing, turning genes on and off,” says Nielsen. “The ability to engineer this gift of evolution is, in my view, going to be the most meaningful and impactful technology that humans have ever developed.”

Forbes

Harry McNamara PhD ’19, David Heller ’18, and Shara Ticku co-founded C16 Biosciences, a biotechnology company that uses synthetic biology to address environmental concerns, reports John Cumbers for Forbes. The company “wants to replace conflict palm oil with a sustainable alternative made in yeast using precision fermentation,” writes Cumbers.

Bloomberg

Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li-Huei Tsai, has secured a large-scale trial to test a new device aimed at treating Alzheimer’s disease, reports Sarah McBride for Bloomberg.

The Boston Globe

Jake Becraft PhD ’19 and former postdoctoral associate Tasuku Kitada co-founded Strand Therapeutics, a biotech firm developing mRNA therapies for cancer, reports Ryan Cross for The Boston Globe. They created “a way to activate mRNA in the presence of particular microRNAs – a much more useful application for therapies,” writes Cross. 

Wired

Research from Synlogic, a biotech company founded by Profs James Collins and Timothy Lu, has found that it’s the company’s engineered bacteria could provide some benefit to patients with a rare genetic disease, reports Emily Mullin for Wired. “Similar to how you might program a computer, we can tinker with the DNA of bacteria and have them do things like produce a drug at the right time and the right place, or in this case, break down a toxic metabolite,” says Lu.

CNBC

CNBC reporter Catherine Clifford spotlights C16 Biosciences, a startup co-founded by MIT alumni that is developing a palm oil alternative called Palmless. “What we are building is a platform technology that can produce all different kinds of microbial oils,” explains David Heller ’18, co-founder and head of operations at C16 Biosciences. “It’s definitely possible that we’re able to make other kinds of vegetable oil replacements in the future.” 

The Boston Globe

Writing for The Boston Globe, Prof. Linda Griffith underscores the pressing need to invest in studying women’s health and menstruation science. “These were the attitudes society had about breast cancer decades ago; we didn’t talk about it. But then we finally focused on the science, and overcame the squeamishness about mentioning ‘breasts’ by creating a technical language that could be spoken without hesitation by anyone,” writes Griffith. “We need a similar scientific push for menstruation science, and a comfort level with the language that goes with it. It’s time.”