Eric Boodman writes for STAT that MIT researchers have developed a technique to produce biopharmaceuticals in remote locations. “Instead of making the drugs and then trying to keep them refrigerated over thousands of miles,” Boodman writes, the researchers, “want to give people the ingredients. These components don’t require refrigeration, and the instructions are as simple as they come: Just add water.”
Prof. Robert Langer talks to Jessica Harris from NPR about his research on tissue engineering and drug delivery, the commercialization of his discoveries, and the many companies he has started. Langer says he started his lab based off his desire to improve people’s lives by conducting research “at the interface of chemical engineering and medicine.”
Angus Chen reports for NPR that MIT and Harvard researchers have captured footage showing bacteria invading antibiotics and transforming into superbugs. Postdoc Tami Lieberman explains that she hopes the visualization will help illustrate that “drug resistance is not some abstract threat. It's real."
MIT researchers have developed a new way to record the activities of human cells, reports Kevin Hartnett for The Boston Globe. “Most of the studies we do to understand diseases like cancer and Alzheimer’s involve studying cells in a dish. We’re interested in understanding how cells function in their natural environments,” explains Prof. Timothy Lu.
Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a technique to record the history of human cells. “Much of our understanding of cancer is not reflective of what’s going on inside the patient,” explains Prof. Timothy Lu. “It’s only with tools like ours you can start testing those hypotheses.”
MIT researchers have developed a portable system that could produce biotech drugs on demand, reports Lisa Rapaport for Reuters. “The table-top machine has the potential to one day produce proteins to treat any number of a wide range of conditions like cancer, diabetes, heart attacks, and hemophilia,” writes Rapaport.
A portable device developed by MIT researchers uses programmable yeast to create drugs on demand, reports Jamie Ducharme for Boston Magazine. The device “could be a lifesaver for doctors working in vulnerable conditions, such as the battlefield, a remote village, or even an ambulance,” writes Ducharme.
Popular Science reporter Samantha Cole writes that MIT researchers have developed a laptop-sized, portable device that can produce biopharmaceuticals for doctors in remote locations. Cole explains that the device can “produce a single dose of treatment with a series of steps, using genetically engineered yeast cells as a mini 'factory' for a variety of customizable drugs.”
Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a portable pharmacy that can manufacture biopharmaceuticals and modify treatments. “Instead of relying on a cocktail that already exists, you can reprogram the reactor on demand to customize the treatment,” says Prof. Timothy Lu.
Prof. Linda Griffith speaks with Wired reporter Sarah Zhang about her work developing chips that can mimic human organs in an effort to better understand interactions between the immune system and the liver. Griffith is currently working to connect at least 10 miniature organs on a chip to study, for example, how breast cancer can spread to the liver.
MIT researchers have discovered that a bacterium found in the human mouth can be used to form a new CRISPR gene-editing system that can target RNA, reports Carl Zimmer for The New York Times. The development “may open up a new front in gene engineering, gaining the ability to precisely adjust the proteins in cells, for instance, or to target cancer cells."
New Scientist reporter Colin Barras writes that MIT researchers have found they can program C2c2, an enzyme found in bacteria, to serve as an RNA-editing tool. Barras writes that the tool “promises to transform our understanding of RNA’s role in our growth and development, and provide a new avenue for treating infectious diseases and cancer.”
Michael Le Page writes for New Scientist that MIT researchers have developed a technique that allows cells to log their activities using the CRISPR gene-editing system. Le Page explains that “such CRISPR-based logging could have a huge range of uses, from smart cells that monitor our health from within, to helping us understand exactly how our bodies develop.”
In an article for The Huffington Post, Susan Blumenthal highlights how researchers from MIT have developed a paper-based test for diagnosing the Zika virus. Blumenthal writes that “the test consists of a paper covered with yellow dots that turns purple in the presence of the RNA of the virus.”
Huffington Post reporter Carolyn Gregoire writes that MIT spinoff Synlogic is working on reprogramming gut bacteria to act as a living therapeutic. “It’s become really clear that the bacteria living in us and on us affect our bodies in a variety of different ways — in ways that we never imagined,” explains Prof. Timothy Lu.