Writing for the Boston Herald, Lindsay Kalter reports that MIT scientists have built an ingestible capsule that could allow doctors to diagnose gastrointestinal diseases without invasive procedures. Graduate student Mark Mimee explains that the device, “sets the stage for having a pill that can give you a big biochemical profile of the gut related to various diseases.”
Popular Mechanics reporter David Grossman writes that a new ingestible medical device developed by MIT researchers could monitor the health of the human gut. Calling the project “a true team effort,” Grossman explains that it required expertise in biological engineering techniques, electronic circuit design, materials, and gastroenterology.
Professors Edward Boyden and Feng Zhang have been named to the 2018 class of Howard Hughes Medical Institute investigators, reports Jonathan Saltzman for The Boston Globe. “We selected these scientists because they know how to ask hard and interesting questions with skill and intellectual courage,” says David Clapham, vice president and chief scientific officer of the institute.
MIT spinout Ginkgo Bioworks is highlighted on the 2018 CNBC Disruptor 50 list, reports CNBC’s Andrew Zaleski. Zaleski notes that Ginkgo Bioworks, “has developed an automated process for combining genetic parts that has made it the largest designer of printed DNA in the world. That breakthrough has positioned the start-up to change the face of a variety of industries.”
Elise Takahama writes for The Boston Globe that MIT researchers have developed a new technique to create “xenoproteins,” manmade proteins that could be used to battle infectious diseases like Ebola. Unlike drugs developed with natural proteins, the xenoproteins, “are more stable, easier to administer, and manufactured more quickly,” Takahama explains.
Synlogic, founded by Prof. Jim Collins and Associate Prof. Tim Lu, is programming probiotic bacteria to treat certain genetic or acquired metabolic disease, reports Robin Seaton Jefferson for Forbes. One product is used for people whose bodies can’t maintain a healthy level of ammonia and “has been specifically engineered to convert the excess ammonia to a harmless metabolite,” explains Seaton Jefferson.
MIT startup Ministry of Supply has developed a jacket that utilizes AI to keep its wearer warm. “The jacket…can also be voice-controlled through devices like the Amazon Echo or manually with an app,” writes Erin Black for CNBC.
Originally created by the Zhang Lab in 2017, CRISPR tool SHERLOCK has been improved upon to be three times more sensitive for detecting viruses and infections using an inexpensive test strip. Sharon Begley writes for STAT News, “A paper strip, like in a pregnancy test, is dipped into a sample, and if a line appears, the target molecule was detected — no instruments required.”
A gene-editing tool called SHERLOCK, developed in Prof. Feng Zhang’s lab, allows for faster detection of infections and viruses, such as Zika and Dengue fever. “It does this by combining different types of CRISPR enzymes, which are unleashed together to target distinct bits of DNA and RNA, another of the major biological molecules found in all forms of life,” writes Alessandra Potenza for The Verge.
MIT researchers have discovered a new family of viruses in the ocean that appears to play a key role in ocean ecosystems and could help provide insights on how viruses evolve, reports Marin Finucane for The Boston Globe. Finucane explains that the findings could also lead to, "a better understanding of human biology.”
The Boston Globe Magazine highlights two MIT spinoffs in a list spotlighting 19 bold new ideas and fresh faces from 2017. Startup Ministry of Supply, which creates custom apparel using high-tech design, has made “getting a great-fitting blazer...a seamless experience,” while another startup, Biobot, has begun analyzing sewer waste to determine which communities are most affected by opioids.
MIT spinout Ginkgo Bioworks has not only maintained its founding members, but also recently raised $275 million from investors, writes Matthew Herper for Forbes. Herper predicts that excitement surrounding synthetic biology companies will continue because “private money is getting excited about the idea of designing biology.”
MIT researchers have developed a new technique to 3-D print genetically engineered bacteria into a variety of shapes and forms, reports Karen Hao for Quartz. The technique could eventually be used to develop such devices as, “an ingestible living robot that secretes the correct drug when it detects a tumor.”
MIT engineers have developed a method to 3-D print living cells into tattoos and 3-D structures, reports Danny Paez for Inverse. Paez explains that the researchers believe the technique, “could possibly be used to create a ‘living computer,’ or a structure made up of living cells that can do the stuff your laptop can.”
Co.Design reporter Katharine Schwab writes that MIT researchers have developed a tattoo made of living cells that activate when exposed to different kinds of stimuli. Schwab explains that in the future the tattoos could be designed, “so that they respond to environmental pollutants or changes in temperature.”